Our primary purpose is generation of new mouse models for all research groups at Babraham. We specialize in zygotic gene editing which uses lower resources and has a faster turnaround (6 months for validated F1 mice). With zygotic targeting we can create a variety of mouse models such as traditional KO, deletions, point mutations, floxed and Cre-based mouse models. We can also produce more advanced models such genes tagged with Halotag, MiniTurbo, FKBP12F36V and NanoBiT. Further, we can also swap genomic DNA with other organisms to create chimeric DNA mouse models. We can also insert larger DNA sequences (>10kb) into safe harbour sites such as Rosa26 using landing pad technology. Thus, we provide a comprehensive range of mouse models for the institute.
We also provide expertise in:
Asif Nakhuda - Gene Targeting Specialistasif.firstname.lastname@example.org