Research Groups
The Babraham Institute’s research focuses on understanding fundamental biology and its role in healthy ageing and disease. Our research groups form three strategic research programmes; epigenetics, signalling and lymphocyte signalling. You can discover more about all our research groups below.
In addition, we have a number of affiliated research groups and the Institute operates several scientific facilities. Each facility employs a specialist team with skills and expertise in key cutting-edge research techniques.
Geoff Butcher
Lymphocyte SignallingMaintaining the immune cell population through lymphocyte homeostasis and the role of GIMAP proteins in this process
Olivia Casanueva
EpigeneticsMechanisms linked to stress and ageing in C. elegans worms and how they vary between individuals
Simon Cook
SignallingThe role of protein kinases in cellular responses to growth factors, nutrient availability or stress and damage
Anne Corcoran
Lymphocyte SignallingUnderstanding the role of chromatin and nuclear organisation in controlling gene expression during the development of the immune system
Oliver Florey
SignallingThe role of autophagy and other cellular ‘eating’ processes in normal biology and during ageing or disease
Phill Hawkins
SignallingThe molecular mechanisms and physiological significance of signalling networks involving phosphoinositide 3-kinases (PI3Ks)
Gavin Kelsey
EpigeneticsThe epigenetics of the egg and sperm and their role in carrying information between generations
Nicholas Ktistakis
SignallingHow autophagy contributes to health and healthy ageing by eliminating damage and recycling cell components
Michelle Linterman
Lymphocyte SignallingUnderstanding the changes that occur in T cells with age that contribute to the age-dependent decline in the germinal centre response
Adrian Liston
Lymphocyte SignallingThe role of regulatory T cells in controlling and suppressing the immune system and the effect of age on these cells
Wolf Reik
EpigeneticsThe role of epigenetics in cell identity and factors involved in the process of epigenetic reprogramming
Claudia Ribeiro de Almeida
Lymphocyte SignallingThe molecular mechanisms underlying diversification of antibody genes by B cells in the immune system
Sarah Ross
Lymphocyte SignallingThe effect of factors like oxygen levels on gene expression and regulation in T cells of the immune system
Rahul Roychoudhuri
Lymphocyte SignallingHow tolerance mechanisms in the immune system help to prevent autoimmunity and allergies, and their use in therapies
Peter Rugg-Gunn
EpigeneticsThe epigenome in stem cells and development, and how epigenetics changes through the life course
Stefan Schoenfelder
EpigeneticsThe functional organisation of the genome in three dimensions (Dr Schoenfelder is an independent Career Progression Fellow)
Len Stephens
SignallingThe molecular mechanisms and physiological significance of signalling networks involving phosphoinositide 3-kinases (PI3Ks)
Martin Turner
Lymphocyte SignallingGene expression and the roles of RNAs in the development and function of lymphocytes
Michael Wakelam
SignallingUnderstanding the essential physiological functions of lipids particularly during healthy ageing
Heidi Welch
SignallingControl of cell shape, movement, gene expression and other factors by Rac-GEF proteins