Life Sciences Research for Lifelong Health

The Babraham Institute undertakes world-leading research into understanding the biology of how our bodies work, including what changes as we age and during disease. Our research is split into four programmes: Epigenetics, Signalling, Lymphocyte Signalling and Nuclear Dynamics, supported by strategic programme grants from the Biotechnology and Biological Sciences Research Council (BBSRC) and additional funding from research councils, the EU and charities.

We maximise the impact of our research through Knowledge Exchange, Commercialisation and Public Engagement activities. We do this by collaborating with other academics, policy makers, charities, schools, the general public and industry, including companies on the Babraham Research Campus. Commercialisation is achieved in collaboration with the Institute’s wholly-owned trading arm, Babraham Institute Enterprise Limited.


Placenta defects key factor in prenatal deaths

Almost 70% of genes linked to prenatal death could affect the placenta

Of 103 mutations that lead to prenatal death in mice, 68% caused…


Making new contacts: Super-enhancers in changing cells

Changing DNA organisation changes gene activity between cell types

Super-enhancers contact different genes in different cell types


Genes for age-linked brain deterioration identified

One gene led to premature cell ageing and could reveal ways to slow brain ageing

A group of 250 genes contribute to aging in brain stem cells

Access our Science Services

Biological Chemistry
Biological Support Unit
Flow Cytometry
Mass Spectrometry
Gene Targeting
Biological Chemistry
Biological chemistry is the interface between chemistry and biology, requiring both synthetic organic chemistry skills and a knowledge of biochemistry
We have established methods to analyse neutral lipids, phospholipids and sphingolipids using a Shimadzu IT-TOF mass spectrometer coupled to a Prominence HPLC system
Biological Support Unit
Our state-of-the-art Biological Support Unit provides housing and care for pathogen-free rodents used in the academic research programmes and by private companies
Flow Cytometry
The Babraham Institute Flow Cytometry Core Facility offers high quality service and state-of-the-art instrumentation to members of Babraham Institute and external users.
Mass Spectrometry
The Mass Spectrometry Facility is housed in a purpose-built laboratory in a new building in the centre of the campus
Gene Targeting
Providing a complete service to generate genetically altered mouse strains for Babraham Institute research groups and external companies
The bioinformatics group provides an interface between the computational infrastructure of the insitute and the biology performed within the research groups
The Facility plays a crucial role in all the Institute’s research programmes and is also available to external users on a fee-for-service basis

The Imaging Facility provides supported access to advanced fluorescence imaging technologies and image analysis solutions.


Optical control of T-cell signalling dynamics

Dr John James

Department of Medicine, University of Cambridge


Identifying new gene regulating networks in immune cells

Dr Elke Glasmacher

Roche Innovation Centre, Munich, Germany


Cellular recycling: role of autophagy in aging and disease

Prof. Malene Hansen

Sanford Burnham Prebys Medical Discovery Institute, Program…


Chromos at ZKM 'Open Codes' Exhibition

Find Chromos virtual reality (VR) experience in Karlsruhe, Germany


Race Against the Ageing Clock

Get hands-on with exciting research with the Babraham Institute at their newest epigenetics exhibition

Part of the Cambridge Science Festival


Key visitor pages


The following pages may be of particular interest to those in the Academic community:


Members of the media and journalists may wish to visit the following sections for further details about our work:


Members of the public may wish to look at the following pages to find out how the Babraham Institute works with and for society:

Gene expression hallmarks of cellular ageing.

Frenk S, Houseley J

1573-6768: (2018)

PMID: 29492790

Neuronal Cell Death.

Fricker M, Tolkovsky AM, Borutaite V

Physiological reviews
98 1522-1210:813-880 (2018)

PMID: 29488822