We make discoveries that help us understand human biology and improve lifelong health

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Studying the biology of ageing to help us live healthier lives

The Babraham Institute is a life science research institute dedicated to making the fundamental discoveries needed to maintain health and improve wellbeing throughout life. Our ground-breaking research in human biology sparks the innovative advances which will improve and protect lifelong health.

Our research is split into three programmes: Epigenetics, Signalling, and Immunology, supported by nine scientific facilities. 
 

Explore our Research   Explore our facilities

Working transparently and collaboratively to share our science for maximum impact

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.

Yshii L, Pasciuto E, Bielefeld P, Mascali L, Lemaitre P, Marino M, Dooley J, Kouser L, Verschoren S, Lagou V, Kemps H, Gervois P, de Boer A, Burton OT, Wahis J, Verhaert J, Tareen SHK, Roca CP, Singh K, Whyte CE, Kerstens A, Callaerts-Vegh Z, Poovathingal S, Prezzemolo T, Wierda K, Dashwood A, Xie J, Van Wonterghem E, Creemers E, Aloulou M, Gsell W, Abiega O, Munck S, Vandenbroucke RE, Bronckaers A, Lemmens R, De Strooper B, Van Den Bosch L, Himmelreich U, Fitzsimons CP, Holt MG, Liston A 26 May 2022, PMID: 35618831 Nature immunology

Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin.

Spaan AN, Neehus AL, Laplantine E, Staels F, Ogishi M, Seeleuthner Y, Rapaport F, Lacey KA, Van Nieuwenhove E, Chrabieh M, Hum D, Migaud M, Izmiryan A, Lorenzo L, Kochetkov T, Heesterbeek DAC, Bardoel BW, DuMont AL, Dobbs K, Chardonnet S, Heissel S, Baslan T, Zhang P, Yang R, Bogunovic D, Wunderink HF, Haas PA, Molina H, Van Buggenhout G, Lyonnet S, Notarangelo LD, Seppänen MRJ, Weil R, Seminario G, Gomez-Tello H, Wouters C, Mesdaghi M, Shahrooei M, Bossuyt X, Sag E, Topaloglu R, Ozen S, Leavis HL, van Eijk MMJ, Bezrodnik L, Blancas Galicia L, Hovnanian A, Nassif A, Bader-Meunier B, Neven B, Meyts I, Schrijvers R, Puel A, Bustamante J, Aksentijevich I, Kastner D, Torres VJ, Humblet-Baron S, Liston A, Abel L, Boisson B, Casanova JL 19 May 2022, PMID: 35587511 Science
Houseley Lab 2018

The Babraham Institute offers a dynamic and diverse place of employment. Our excellent training activities allow us to attract and retain the best PhD students, postdoctoral scientists, research fellows and staff across all parts of the Institute.

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The Babraham Institute in three minutes (and a bit)

Our animated introduction - find out about who we are, what our research is about and how we share our discoveries to improve lifelong health and wellbeing.