Inhibition of Phosphoinositide 3-Kinase p110delta Does Not Affect T Cell Driven Development of Type 1 Diabetes Despite Significant Effects on Cytokine Production.
Barbera Betancourt A, Emery JL, Recino A,
11 1932-6203: ( 2016 )
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
F Ramadani, DJ Bolland, F Garcon,
3 134: ( 2010 )
MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells.
RJ Salmond, J Emery, K Okkenhaug,
Journal of immunology (Baltimore, Md. : 1950)
183 11: ( 2009 )
Proliferative signals mediated by CD28 superagonists require the exchange factor Vav1 but not phosphoinositide 3-kinase in primary peripheral T cells.
T Gogishvili, F Elias, JL Emery,
European journal of immunology
38 9: ( 2008 )
CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.
111 3: 2008