01/06/2014
The Babraham Institute is hosting a one day meeting on Monday 23rd June 2014 from 10am – 6pm on ‘PI3-Kinases in Immunity, Inflammation and Infection’. The event is open to all research scientists, PhD students, postdocs and PIs with an interest in PI3-kinase research. A plenary lecture will be given by Dr Roger Williams from the MRC-Laboratory of Molecular Biology on ‘The Structure and Function of PI3-Kinase Isoforms. This lecture will be followed by a series of short talks, poster session and BBQ.
09:15 – 10:00 Registration 10:00 – 10:30 Roger Williams, MRC-LMB The structure and function of PI3-Kinase isoforms 10:30 – 10:45 Alison Condliffe, University of Cambridge Activated PI3-Kinase delta syndrome, a newly described immune deficiency syndrome 10:45 – 11:00 Nital Sumaria, Blizard Institute, QMUL A requirement for PI3-Kinase in gamma delta T cell development 11:00 – 11:15 Jean-Marc Doisne, University of Cambridge Immunomodulation of selective naïve T cell functions by p110. Inactivation improves the outcome of allogeneic hematopoietic cell transplantation 11:15 – 11:30 Amy MacQueen, Babraham Institute Differential roles for the Class IA PI3-Kinases p110α and p110δ in T cell activation 11:30 – 12:00 Coffee 12:00 – 12:15 David Finlay, Trinity College Dublin mTORC1-dependent metabolic reprogramming is a prerequisite for pro-inflammatory natural killer cell functions 12:15 – 12:30 Esther Castellano-Sanchez, Bart’s Cancer Institute QMUL Understanding the role of Ras-PI3-Kinase signalling in lung cancer tumour associated macrophage recruitment 12:30 – 12:45 Priyanka Tibarewal, Heriot-Watt University Edinburgh Dissection of PTEN mediated tumour suppression in whole-body and T cell specific transgenic mice 12:45 – 13:00 Yohei Ohashi, MRC-LMB Characterisation of a new subunit of the Class III PI3-Kinase complex 1 13:00 – 14:00 Lunch 14:00 – 14:15 Mark Coles, University of York Essential role for PI3-Kinase dependent chemotaxis in neutrophil dynamics in tissue draining lymph nodes 14:15 – 14:30 Georgia Walton, University of Birmingham Abnormal neutrophil migration is a feature of early COPD and causally related to increased PI3-Kinase signalling 14:30 – 14:45 Arnaud Deladeriere, Babraham Institute PI3-Kinase gamma regulatory subunits control different neutrophil functions 14:45 – 15:00 Malcolm Begg, GSK The effect of a novel PI3-Kinase delta inhibitor on PIP3 levels in sputum from the lungs of healthy smokers 15:00 – 15:15 Coffee 15:15 – 15:30 Tom Blair, University of Bristol Redundant roles of PI3-Kinase isoforms p110α and p110β in primer-mediated platelet potentiation 15:30 -15:45 Ezra Aksoy, William Harvey Research Institute, QMUL The isoform selective role of PI3-Kinases in crystal uptake and inflammasome-mediated disease 15:45 – 16:00 Jennifer Ball, University of Bath Effect of pharmacological targeting of SHIP on activation, adhesion and migration of human T lymphocytes 16:00 – 16:15 Chris Rudd, University of Cambridge PI3-Kinase in T-cells; a role in CD28 priming of antigen receptor responses 16:15 – 17:30 Poster Session and Drinks 17:30 BBQ
01 June 2014