UK Proteostasis Conference

UK Proteostasis Conference

UK Proteostasis Conference

Della David & Oliver Florey (Babraham Institute)
Laura Itzhaki & Ritwick Sawarkar (University of Cambridge).

Confirmed speakers:

  • Rick Morimoto (Keynote speaker), Department of Molecular Biosciences, Northwestern University and Royal Society Wolfson Visiting Fellow at the University of Cambridge – The Proteostasis Network as a Biological Clock for Health, Aging and Disease
  • Ivana Bjedov, Molecular Biology of Cancer Research Group, UCL Cancer Institute – Protein phase transitions
  • Bernadette Carroll, School of Biochemistry, University of Bristol – Dysregulated proteostasis as a virulence mechanism of pathogenic bacteria, the case of the Mycobacterium ulcerans exotoxin mycolactone
  • Pedro Carvalho, Sir William Dunn School of Pathology, University of Oxford – The challenges of predicting amyloidogenicity
  • Benedict Cross, PhoreMost, Cambridge – Exploring lysosomal dysfunction in cellular senescence
  • Tuomas Knowles, Department of Chemistry, University of Cambridge – How neuronal signalling connects perception with proteostasis and ageing
  • Sheena Radford, Faculty of Biological Sciences, University of Leeds – Diverse ubiquitin chain topologies orchestrate plant immune signalling
  • Rahul Samant, Babraham Institute, Cambridge – Induced control of protein degradation
  • Steven Spoel, Institute of Molecular Plant Sciences, University of Edinburgh – Discovery and development of NXP800: a clinical stage GCN2/ISR activator that inhibits HSF1 transcription for the treatment of ARID1A mutant ovarian cancer
  • Rachel Simmonds, Department of Microbial Sciences, University of Surrey – Increased fidelity of protein synthesis extends lifespan
  • Rebecca Taylor, School of Biological Sciences, University of East Anglia – title to be confirmed
  • Paul Workman, Signal Transduction & Molecular Pharmacology team, Institute of Cancer Research – Deconvoluting cellular proteostasis strategies across proliferative states


Panel discussion on day 2: How can our knowledge of proteostasis be translated into therapeutic benefit?

Chaired by Kathryn Chapman, Director, Science & Entrepreneurship at Babraham Research Campus


  • Paul Thompson, Chief Scientific Officer, Mission Therapeutics
  • Fiona Menzies, Associate Vice President, Eli Lilly and Company
  • James Hunt, R&D Biologics Engineering, AstraZeneca
  • Wei-Li (William) Kuan, Head of Biology of the Alborada Drug Discovery Institute, University of Cambridge
  • Ralph Minter, Senior Vice President Research, Alchemab


See the full programme and register at:

Registration closes on 24th April 2024.


Find out more about the UK Proteostasis Network:


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