Life Sciences Research for Lifelong Health

28/04/2016

Stem cells know how to open up and unwind

Open genome structure important for embryonic stem cells

Paper published in Genes & Development


22/04/2016

The importance of resting phases in B cell development

Role of RNA binding proteins discovered

Paper published in Science


17/03/2016

Understanding immune cell biology to improve vaccination response

How T follicular regulatory cells form after vaccination

Paper published in Nature Communications


05/05/2016

Optical superresolution microscopy of molecular mechanisms of disease

Prof. Clemens F. Kaminski - University of Cambridge


11/05/2016

More than Refinement – improving the validity of animal research

Prof Hanno Würbel - University of Bern, Switzerland


12/05/2016

Genome manipulation using CRISPR technology

Dr Mark Hodson - GE Healthcare

Science Services

Bioinformatics
Biological Chemistry
Biological Support Unit
Flow Cytometry
Gene Targeting
Imaging
Lipidomics
Mass Spectrometry
Sequencing
Bioinformatics

The bioinformatics group provide biological computing services for the research groups at the institute but also for companies both on site and further afie...

Biological Chemistry
Biological chemistry is the interface between chemistry and biology, requiring both synthetic organic chemistry skills and a knowledge of biochemistry.

Typic...
Biological Support Unit
Our state-of-the-art Biological Support Unit (BSU) opened in 2009 and provides housing and care for pathogen-free rodents used in both the academic scientific research pr...
Flow Cytometry
Providing a world-class flow cytometry facility to help meet our scientific research goals.
 
The Babraham Institute Flow Cytometry Core Facility offers ...
Gene Targeting
The Babraham Gene Targeting Facilities (GTF) provides a complete service to generate genetically altered mouse strains for Babraham Institute researchers and external inv...
Imaging

The Imaging Facility is located within one of the research buildings of the Babraham Institute and is equipped with state-of-the-art commercial imaging tech...

Lipidomics
The Lipidomics Mass Spectrometry Facility at Babraham Institute was established by Prof. Michael Wakelam and Dr. Qifeng Zhang at the beginning of 2007.

Since...
Mass Spectrometry
The Babraham Institute Mass Spectrometry Facility is housed in a purpose-built laboratory in a new building in the centre of the campus.

The primary role of ...
Sequencing
Whilst the Human Genome Project sequenced the first complete human genome over the course of fifteen years and a cost of more than 2 billion US dollars, the advent of Nex...

Much of the work of the Babraham Institute focuses on the BBSRC’s strategic objective of research into healthy ageing – understanding the basic molecular processes to promote lifelong health and wellbeing.

Research into ageing is carried out across the Institute’s four programme areas: Epigenetics, Signalling, Lymphocyte Signalling and Nuclear Dynamics, and these work in close collaboration with each other. The four programme areas are funded by the BBSRC as Institute Strategic Programme Grants (ISPG).

 

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RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

Galloway A, Saveliev A, Łukasiak S

Science (New York, N.Y.)
352 1095-9203:453-9 (2016)

PMID: 27102483

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Clark SJ, Lee HJ, Smallwood SA

Genome biology
17 1474-760X:72 (2016)

PMID: 27091476