Life Sciences Research for Lifelong Health

25/01/2016

Mum’s in control – even before you’re born

Egg’s epigenetic ‘blueprint’ important for placenta development in pregnancy

Paper published in Developmental Cell


25/01/2016

Institute delivers taste of lab research for UTC Cambridge students

Project offers “sheer enjoyment of discovery”

Lord Baker meets researchers and project participants


11/01/2016

New method allows study of DNA methylation and gene expression in the same cell

Method reveals new epigenome-transcriptome associations

Technique described in Nature Methods


14/02/2016

Weapons of Microscopic Destruction at the Brighton Science Festival

Brighton Science Festival - 13th and 14th February


16/02/2016

NF-κB: a master regulator of the cellular response to stress and infection

Prof Neil Perkins - Institute for Cell and Molecular Biosciences…


18/02/2016

B cell trafficking and activation in the splenic environment

Dr Tal Arnon - The Kennedy Institute of Rheumatology, University…

Science Services

Bioinformatics
Biological Chemistry
Biological Support Unit
Flow Cytometry
Gene Targeting
Imaging
Lipidomics
Mass Spectrometry
Sequencing
Bioinformatics

The bioinformatics group provide biological computing services for the research groups at the institute but also for companies both on site and further afie...

Biological Chemistry
Biological chemistry is the interface between chemistry and biology, requiring both synthetic organic chemistry skills and a knowledge of biochemistry.

Typic...
Biological Support Unit
Our state-of-the-art Biological Support Unit (BSU) opened in 2009 and provides housing and care for pathogen-free rodents used in both the academic scientific research pr...
Flow Cytometry
Providing a world-class flow cytometry facility to help meet our scientific research goals.
 
The Babraham Institute Flow Cytometry Core Facility offers ...
Gene Targeting
The Babraham Gene Targeting Facilities (GTF) provides a complete service to generate genetically altered mouse strains for Babraham Institute researchers and external inv...
Imaging

The Imaging Facility is located within one of the research buildings of the Babraham Institute and is equipped with state-of-the-art commercial imaging tech...

Lipidomics
The Lipidomics Mass Spectrometry Facility at Babraham Institute was established by Prof. Michael Wakelam and Dr. Qifeng Zhang at the beginning of 2007.

Since...
Mass Spectrometry
The Babraham Institute Mass Spectrometry Facility is housed in a purpose-built laboratory in a new building in the centre of the campus.

The primary role of ...
Sequencing
Whilst the Human Genome Project sequenced the first complete human genome over the course of fifteen years and a cost of more than 2 billion US dollars, the advent of Nex...

Much of the work of the Babraham Institute focuses on the BBSRC’s strategic objective of research into healthy ageing – understanding the basic molecular processes to promote lifelong health and wellbeing. Research into ageing is carried out across the Institute’s four programme areas: Epigenetics, Signalling, Lymphocyte Signalling & Development and Nuclear Dynamics, and these work in close collaboration with each other. The four programme areas are funded by the BBSRC as Institute Strategic Programme Grants (ISPG).

 

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HiCUP: pipeline for mapping and processing Hi-C data.

Wingett S, Ewels P, Furlan-Magaril M

F1000Research
4 2046-1402:1310 (2015)

PMID: 26835000

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells.

Aloulou M, Carr EJ, Gador M

Nature communications
7 2041-1723:10579 (2016)

PMID: 26818004

Maternal DNA Methylation Regulates Early Trophoblast Development.

Branco MR, King M, Perez-Garcia V

Developmental cell
36 1878-1551:152-63 (2016)

PMID: 26812015