Life Sciences Research for Lifelong Health

Postdoctoral Research Scientist


We are looking for a proficient and highly motivated Postdoctoral Research Scientist to lead research projects to investigate epigenetic mechanisms in early mammalian development. The successful candidate will join Wolf Reik’s team within the Epigenetics Programme. The Epigenetics Programme has major strengths in applying low cell number and single cell epigenomic assays to a wide range of questions in developmental and ageing biology.
The successful candidate will work to identify new epigenetic regulators involved in lineage priming and cell fate choice particularly in in vitro differentiation systems of pluripotent stem cells. The postholder will establish cell lines with tagged candidate proteins as well as auxin degradable ones, and will carry out biochemical characterisation of protein complexes, and will further characterise the cells using epigenomic approaches including single cell ones.
The postholder will also establish a CRISPR/cas9 based screen for novel priming factors. The overall significance of this work will be to characterise the molecular basis for multi-lineage priming in pluripotent stem cells.
The ideal candidate must have a PhD in developmental biology, molecular biology, genetics or related biological discipline and must be able to demonstrate experience in molecular biology including the preparation of RNA-seq, ChIP-seq and RIME libraries. Extensive knowledge of cell biology and epigenetics research are essential. Previous experience with low cell number epigenetic and transcriptional techniques is desirable.
The funding for this position is available for three years in the first instance.

Starting salary is £30,751 per annum to £32,116 per annum depending on experience.
For more information on the work of the group, please visit:
Full details of the position can be found here.
On applying please quote reference WR-PRS-LTC.
Closing date for completed applications is Friday, 31 August 2018.

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The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer. 

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