Elizabeth Hampson
Elizabeth studied Biochemistry at Bristol University with a year spent working at AstraZeneca in Cambridge.She is investigating GPCR trafficking control by P-Rex Rac-GEFs.
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Latest Publications
PtdIns(3,4,5)P-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Srijakotre N, Liu HJ, Nobis M,
Proceedings of the National Academy of Sciences of the United States of America
1
1:
(
23 Oct 2020
)
PMID: 33097662
Removing physiological motion from intravital and clinical functional imaging data.
Warren SC, Nobis M, Magenau A,
eLife
7
2050-084X:
(
2018
)
PMID: 29985127
Rac-GTPases and Rac-GEFs in neutrophil adhesion, migration and recruitment.
Pantarelli C, Welch HCE,
European journal of clinical investigation
1365-2362:
(
2018
)
PMID: 29682742
A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
Nobis M, Herrmann D, Warren SC,
Cell reports
21
2211-1247:
(
2017
)
PMID: 28978480
Platelets in neutrophil recruitment to sites of inflammation.
Current opinion in hematology
1531-7048:
2016
PMID: 27820736
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Proceedings of the National Academy of Sciences of the United States of America
1091-6490:
2016
PMID: 26884185
Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
The Journal of biological chemistry
1083-351X:
2016
PMID: 26792863
Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment.
Current opinion in hematology
23
1531-7048:
2016
PMID: 26619317
The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment.
Small GTPases
2154-1256:
2015
PMID: 26103062
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Blood
1528-0020:
2014
PMID: 25538043
A rac1-independent role for p-rex1 in melanoblasts.
The Journal of investigative dermatology
135
1523-1747:
2015
PMID: 25075639