Louis completed his Master’s degree in Bioscience Engineering, Cell and Gene Biotechnology at the University of Ghent. His master thesis titled “Our aging genome: CpG decay throughout human evolution”, studied the impact of DNA methylation on the mutational burden in the human genome.

Continuing the work performed in his master thesis, he started a PhD (partly combined with an educational assignment) at BIOBIX, the research unit for  Bioinformatics and Computational Genomics at the Department of Data Analysis and Mathematical Modelling, University of Ghent. The topic of the PhD considers DNA methylation as a driver of (epi)mutations and the consequences thereof in health, developmental and evolutionary applications. As part of this PhD project, Louis joined the Babraham Institute for an internship focusing on data analysis of 10X Multiome sequencing data of pluripotent stages in early human development.