Life Sciences Research for Lifelong Health

Emma Duncan

Emma comes from Lincolnshire and did her degree in Human Biology at Loughborough University, followed by a masters in Molecular Biology at the University of Nottingham. She moved down to London in 2010 to become a research assistant for a couple of years at Queen Mary University of London, where she worked on the regulation of cholesterol biosynthesis with Prof Carol Shoulders.

Emma stayed at Queen Mary University for another 4 years to do a PhD with Prof Paul Chapple, where she identified that cell organelle defects and disruptions to protein homeostasis are implicated in a rare cerebellar ataxia.

She is now in her first post-doc position with Simon where she is investigating the role that DYRKs have in the regulation of the signalling scaffold protein p62/SQSTM1, which is important for autophagy, nutrient sensing and cellular stress responses.

Outside work Emma enjoys many sports including cycling, rock climbing, swimming and running. 

Latest Publications

Visualisation of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe.

Sipthorp J, Lebraud H, Gilley R

Bioconjugate chemistry
1520-4812: (2017)

PMID: 28449575

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence.

Galloway A, Saveliev A, Łukasiak S

Science (New York, N.Y.)
352 1095-9203:453-9 (2016)

PMID: 27102483

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.

Lochhead PA, Clark J, Wang LZ

Cell cycle (Georgetown, Tex.)
15 1551-4005:506-18 (2016)

PMID: 26959608

Maternal DNA Methylation Regulates Early Trophoblast Development.

Branco MR, King M, Perez-Garcia V

Developmental cell
36 1878-1551:152-63 (2016)

PMID: 26812015