Babraham Institute

The double life of autophagy proteins.

Florey O

Nature microbiology
3 2058-5276:1334-1335 (2018)

PMID: 30478385

Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells.

Bussi C, Peralta Ramos JM, Arroyo DS

Journal of cell science
1477-9137: (2018)

PMID: 30404831

The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.

Rai S, Arasteh M, Jefferson M

Autophagy
1554-8635:1-14 (2018)

PMID: 30403914

The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes.

Fletcher K, Ulferts R, Jacquin E

The EMBO journal
1460-2075: (2018)

PMID: 29317426

Mitosis can drive cell cannibalism through entosis.

Durgan J, Tseng YY, Hamann JC

eLife
6 2050-084X: (2017)

PMID: 28693721

Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation.

Jacquin E, Leclerc-Mercier S, Judon C

Autophagy
1554-8635:1-14 (2017)

PMID: 28296541

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.

Krishna S, Palm W, Lee Y

Developmental cell
38 1878-1551:536-47 (2016)

PMID: 27623384

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy.

Russell MR, Lerner TR, Burden JJ

Journal of cell science
1477-9137: (2016)

PMID: 27445312

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A

Autophagy
12 1554-8635:1-222 (2016)

PMID: 26799652

V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation.

Florey O, Gammoh N, Kim SE

Autophagy
1554-8635:0 (2014)

PMID: 25484071

SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.

Durgan J, Tao G, Walters MS

EMBO reports
16 1469-3178:87-96 (2015)

PMID: 25394671

Competition between human cells by entosis.

Sun Q, Luo T, Ren Y

Cell research
24 1748-7838:1299-310 (2014)

PMID: 25342560

Life Sciences Research for Lifelong Health