Life Sciences Research for Lifelong Health

Elise Jacquin

Elise graduated in 2009 with an MSc in Biochemistry, Cellular and Molecular biology from the University of Besancon, France. She was awarded her PhD in 2013 after studying molecular markers of precancerous and cancerous lesions associated with Human Papillomaviruses. Meanwhile, she worked on the characterization of an alternative pathway of carcinogenesis involving the uptake of apoptotic HPV-positive cancer cells by human primary fibroblasts. This last experience led Elise to grow an interest in macroendocytic processes and their consequences in cells. Elise joined Oliver Florey’s lab in October 2014 for her postdoctoral training funded by Cancer Research UK. She currently investigates the molecular mechanisms which underlie the unconventional activity of autophagy proteins during macroendocytic processes such as phagocytosis and entosis. Since she has joined the lab, Elise has presented her work during meetings in the UK, in Spain and in France.

Latest Publications

Mitosis can drive cell cannibalism through entosis.

Durgan J, Tseng YY, Hamann JC

6 2050-084X: (2017)

PMID: 28693721

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.

Krishna S, Palm W, Lee Y

Developmental cell
38 1878-1551:536-47 (2016)

PMID: 27623384

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy.

Russell MR, Lerner TR, Burden JJ

Journal of cell science
1477-9137: (2016)

PMID: 27445312

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A

12 1554-8635:1-222 (2016)

PMID: 26799652

V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation.

Florey O, Gammoh N, Kim SE

1554-8635:0 (2014)

PMID: 25484071

SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.

Durgan J, Tao G, Walters MS

EMBO reports
16 1469-3178:87-96 (2015)

PMID: 25394671

Competition between human cells by entosis.

Sun Q, Luo T, Ren Y

Cell research
24 1748-7838:1299-310 (2014)

PMID: 25342560

Competition between human cells by entosis.

Sun Q, Luo T, Ren Y

Cell research
24 1748-7838:1299-310 (2014)

PMID: 25342560

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

N Gammoh, O Florey, M Overholtzer

Nature structural & molecular biology
20 2:144-9 (2013)

DOI: 10.1038/nsmb.2475

PMID: 23262492

Autophagy proteins in macroendocytic engulfment.

O Florey, M Overholtzer

Trends in cell biology
22 7:374-80 (2012)

DOI: 10.1016/j.tcb.2012.04.005

PMID: 22608991