Iain Hay
Originally from the Kingdom of Scotland, Iain completed a BSc in Molecular & Cellular Biology at the University of Glasgow. Heading south in search of warmer climes, Iain joined the 4-year PhD programme at the Cambridge Institute for Medical Research. After 3 rotation projects which earned him an MRes in Medical Science, he elected to stay in the Sharpe Lab to complete his PhD project.
His work focuses on using structural and biochemical techniques to investigate the mechanism of tyrosine phosphatase activity; with a particular focus on those which harbour non-canonical enzymatic motifs.
Outside of work, Iain can be found rowing on the Cam or playing guitar in Cambridge’s most mediocre cover band.
Latest Publications
Ighilahriz M, Benfodda M, Sharpe H
Journal of the European Academy of Dermatology and Venereology : JEADV
1468-3083: (2019)
PMID: 31187903
Fearnley GW, Young KA, Edgar JR
eLife
8 2050-084X: (2019)
PMID: 30924770
Sharpe HJ, de Sauvage FJ
Science signaling
11 1937-9145: (2018)
PMID: 29438011
Sharpe H
eLife
5 2050-084X: (2016)
PMID: 27885984
Bonilla X, Parmentier L, King B
Nature genetics
48 1546-1718:398-406 (2016)
PMID: 26950094
Sharpe HJ, Wang W, Hannoush RN
Nature chemical biology
11 1552-4469:246-55 (2015)
PMID: 25785427
Sharpe HJ, Pau G, Dijkgraaf GJ
Cancer cell
27 1878-3686:327-41 (2015)
PMID: 25759019
Basset-Seguin N, Sharpe HJ, de Sauvage FJ
Molecular cancer therapeutics
14 1538-8514:633-41 (2015)
PMID: 25585509
Herzig Y, Sharpe HJ, Elbaz Y
PLoS biology
10 1545-7885:e1001329 (2012)
PMID: 22629230
Sharpe HJ, de Sauvage FJ
Nature chemical biology
8 1552-4469:139-40 (2012)
PMID: 22257852
Sharpe HJ, Stevens TJ, Munro S
Cell
142 1097-4172:158-69 (2010)
PMID: 20603021
Strisovsky K, Sharpe HJ, Freeman M
Molecular cell
36 1097-4164:1048-59 (2009)
PMID: 20064469