Life Sciences Research for Lifelong Health
Roychoudhuri Group members

Charlotte Imianowski

Charlotte graduated in 2016 with a BA in Cell and Systems Biology from the University of Oxford. Her research involved interrogating the function of a tumour suppressor gene in colorectal cancer.

Subsequently, she worked as a Research Assistant in Professor Bass Hassan’s group at the Sir William Dunn School of Pathology, University of Oxford. Her projects have included validating a CRISPR-Cas9 approach to target a gene of interest in Ewing’s Sarcoma, and developing a method for diagnosing Ewing’s Sarcoma using liquid biopsies.

Charlotte is now undertaking a PhD in Rahul Roychoudhuri’s lab, targeting immunosuppressive functions of regulatory T cells in cancer.

Latest Publications

Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors.

Miura Y, Morooka M, Sax N

Journal of immunology (Baltimore, Md. : 1950)
1550-6606: (2018)

PMID: 29540581

Epigenetic control of CD8+ T cell differentiation.

Henning AN, Roychoudhuri R, Restifo NP

Nature reviews. Immunology
1474-1741: (2018)

PMID: 29379213

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.

Afzali B, Grönholm J, Vandrovcova J

Nature immunology
1529-2916: (2017)

PMID: 28530713

BACH transcription factors in innate and adaptive immunity.

Igarashi K, Kurosaki T, Roychoudhuri R

Nature reviews. Immunology
1474-1741: (2017)

PMID: 28461702

Ionic immune suppression within the tumour microenvironment limits T cell effector function.

Eil R, Vodnala SK, Clever D

Nature
537 1476-4687:539-543 (2016)

PMID: 27626381

Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.

Clever D, Roychoudhuri R, Constantinides MG

Cell
166 1097-4172:1117-1131.e14 (2016)

PMID: 27565342

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.

Roychoudhuri R, Clever D, Li P

Nature immunology
1529-2916: (2016)

PMID: 27158840

The transcription factor BACH2 promotes tumor immunosuppression.

Roychoudhuri R, Eil RL, Clever D

The Journal of clinical investigation
1558-8238: (2016)

PMID: 26731475

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.

Sukumar M, Liu J, Mehta GU

Cell metabolism
1932-7420: (2015)

PMID: 26674251