Anne CorcoranAnne Corcoran received her Ph.D. from University College Dublin, Ireland, and her postdoctoral training from the Kennedy Institute of Rheumatology, London (UK) and the Laboratory of Molecular Biology, Cambridge (UK). She joined the Babraham Institute, Cambridge (UK) as a tenure-track group leader, and is currently a senior Group Leader in the Lymhocyte Signalling Laboratory.
Her research focuses on the epigenetic and nuclear organisational mechanisms underpinning immunoglobulin recombination and B cell development. Most recently, her group have developed a next generation sequencing method to interrogate antibody repertoires at the DNA level.
The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF.
Ciccone DN, Namiki Y, Chen C
The Journal of biological chemistry
Hill DL, Pierson W, Bolland DJ
The Journal of experimental medicine
Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.
Koohy H, Bolland DJ, Matheson LS
19 1474-760X:126 (2018)
Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination.
Matheson LS, Bolland DJ, Chovanec P
Frontiers in immunology
8 1664-3224:1550 (2017)
Levin-Klein R, Fraenkel S, Lichtenstein M
8 2041-1723:15575 (2017)
Stubbs TM, Bonder MJ, Stark AK
18 1474-760X:68 (2017)
Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States.
Collier AJ, Panula SP, Schell JP
Cell stem cell
Bolland DJ, Koohy H, Wood AL
15 2211-1247:2475-87 (2016)
Galloway A, Saveliev A, Łukasiak S
Science (New York, N.Y.)
352 1095-9203:453-9 (2016)
AL Duran, P Potter, S Wells
DJ Bolland, MR King, W Reik
Journal of visualized experiments : JoVE
MJ Stubbington, AE Corcoran
Current opinion in genetics & development
23 2:81-8 (2013)