Life Sciences Research for Lifelong Health

Aled Parry

Aled completed his undergraduate degree at the University of Bath before undertaking a PhD at the CRUK Cambridge Institute, where he studied the epigenetic alterations that characterise cellular senescence and cancer.

He joined the Reik group in 2018 where he aims to understand how the epigenetic landscape is established in the early mammalian embryo, with a particular focus on lineage-specific gene regulation and distal regulatory elements.

@aledjohnparry

Latest Publications

Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity.

Hahn O, Stubbs TM, Reik W

PLoS genetics
14 1553-7404:e1007766 (2018)

PMID: 30462643

Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development.

Boroviak T, Stirparo GG, Dietmann S

Development (Cambridge, England)
145 1477-9129: (2018)

PMID: 30413530

5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells.

Raiber EA, Portella G, Martínez Cuesta S

Nature chemistry
1755-4349: (2018)

PMID: 30349137

Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.

Sarker G, Berrens R, von Arx J

Translational psychiatry
8 2158-3188:195 (2018)

PMID: 30315171

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ

Cell systems
2405-4712: (2018)

PMID: 30031774

Defective germline reprogramming rewires the spermatogonial transcriptome.

VasiliauskaitÄ— L, Berrens RV, Ivanova I

Nature structural & molecular biology
25 1545-9985:394-404 (2018)

PMID: 29728652

Dynamics of the epigenetic landscape during the maternal-to-zygotic transition.

Eckersley-Maslin MA, Alda-Catalinas C, Reik W

Nature reviews. Molecular cell biology
1471-0080: (2018)

PMID: 29686419

Correction: Epigenetic resetting of human pluripotency (doi:10.1242/dev.146811).

Guo G, von Meyenn F, Rostovskaya M

Development (Cambridge, England)
145 1477-9129: (2018)

PMID: 29669738

scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.

Clark SJ, Argelaguet R, Kapourani CA

Nature communications
9 2041-1723:781 (2018)

PMID: 29472610

Science Forum: The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES

eLife
6 2050-084X: (2017)

PMID: 29206104