Life Sciences Research for Lifelong Health

Julia Spindel

2015 - current: 1+3 Wellcome Trust Stem Cell and Medicine PhD 
2011-2015: BSc in Biology with Research Abroad at Imperial College London and the ENS de Lyon, France

Latest Publications

Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.

Stuart HT, Stirparo GG, Lohoff T

Cell stem cell
1875-9777: (2019)

PMID: 31422912

Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.

Martin-Herranz DE, Aref-Eshghi E, Bonder MJ

Genome biology
20 1474-760X:146 (2019)

PMID: 31409373

Establishment of porcine and human expanded potential stem cells.

Gao X, Nowak-Imialek M, Chen X

Nature cell biology
21 1476-4679:687-699 (2019)

PMID: 31160711

TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn.

Montalbán-Loro R, Lozano-Ureña A, Ito M

Nature communications
10 2041-1723:1726 (2019)

PMID: 30979904

A single-cell molecular map of mouse gastrulation and early organogenesis.

Pijuan-Sala B, Griffiths JA, Guibentif C

Nature
1476-4687: (2019)

PMID: 30787436

Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program.

Eckersley-Maslin M, Alda-Catalinas C, Blotenburg M

Genes & development
33 1549-5477:194-208 (2019)

PMID: 30692203

Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution.

Messmer T, von Meyenn F, Savino A

Cell reports
26 2211-1247:815-824.e4 (2019)

PMID: 30673604

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.

Gdula MR, Nesterova TB, Pintacuda G

Nature communications
10 2041-1723:30 (2019)

PMID: 30604745

Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity.

Hahn O, Stubbs TM, Reik W

PLoS genetics
14 1553-7404:e1007766 (2018)

PMID: 30462643

Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development.

Boroviak T, Stirparo GG, Dietmann S

Development (Cambridge, England)
145 1477-9129: (2018)

PMID: 30413530

5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells.

Raiber EA, Portella G, Martínez Cuesta S

Nature chemistry
1755-4349: (2018)

PMID: 30349137