Wolf ReikWolf Reik obtained his MD from the University of Hamburg. He did his thesis work with Rudolf Jaenisch, and postdoctoral work with Azim Surani in Cambridge. He became a Fellow of the Lister Institute of Preventive Medicine at Cambridge and subsequently the Head of the Epigenetics Programme at the Babraham Institute in Cambridge and its Associate Director. He is honorary Professor of Epigenetics at the University of Cambridge and Associate Faculty at the Wellcome Trust Sanger Institute, where he is a founding member of the Centre for Single Cell Genomics.
His research interests are in mammalian epigenetics, particularly in epigenetic reprogramming during mammalian development and its role in stem cell biology and inheritance. He has published more than 180 research articles and has an h-factor of 88. He won the Wellcome Prize in Physiology and is a member of EMBO and the Academia Europaea, and a Fellow of the Academy of Medical Sciences and the Royal Society.
Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity.
Linker SM, Urban L, Clark SJ
20 1474-760X:30 (2019)
Eckersley-Maslin M, Alda-Catalinas C, Blotenburg M
Genes & development
33 1549-5477:194-208 (2019)
Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution.
Messmer T, von Meyenn F, Savino A
26 2211-1247:815-824.e4 (2019)
The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome.
Gdula MR, Nesterova TB, Pintacuda G
10 2041-1723:30 (2019)
Hahn O, Stubbs TM, Reik W
14 1553-7404:e1007766 (2018)
Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development.
Boroviak T, Stirparo GG, Dietmann S
Development (Cambridge, England)
145 1477-9129: (2018)
5-Formylcytosine organizes nucleosomes and forms Schiff base interactions with histones in mouse embryonic stem cells.
Raiber EA, Portella G, Martínez Cuesta S
Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.
Sarker G, Berrens R, von Arx J
8 2158-3188:195 (2018)
Rulands S, Lee HJ, Clark SJ
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring.
Sun W, Dong H, Becker AS
Vasiliauskaitė L, Berrens RV, Ivanova I
Nature structural & molecular biology
25 1545-9985:394-404 (2018)
Eckersley-Maslin MA, Alda-Catalinas C, Reik W
Nature reviews. Molecular cell biology