Solenn PatalanoShort Biography
• 2011-current: Post-Doctoral Research Associate, Babraham Institute, Cambridge. (Funded by Wellcome Trust grant)
• 2009-2010: Research Assistant, Institute of Zoology, London (Funded by NERC grant)
• 2008: European PhD in Molecular, Cellular and Developmental Biology, CRG, Barcelona/ Nice. (Fellowship from Spanish Government, EUROBIO recognition for mobility and adaptability in new working environment)
Research Interests and Activities
“Sociogenomic” is a very recent but active field to study social organisation in molecular term. My current research seeks to understand the epigenetic mechanisms underlying genomic regulation and variability across individuals in the context of a social organisation.
My activities focus on the exploration of the dynamic of DNA methylation for the neuronal and behavioural plasticity. I am using two social insect models (the Polistes paper wasp and the Dinoponera Dinosaur ant). Social insects and particularly those organized into simple societies (with few individuals per colony) are interesting groups which retain some trait from their solitary ancestors like flexibility in reproduction behaviour. We are using this natural plasticity of insect societies, their ordinary range of behaviours and their genomes’ simplicity to investigate the mechanisms of the maintenance of phenotypic plasticity.
An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.
Berrens RV, Andrews S, Spensberger D
Cell stem cell
21 1875-9777:694-703.e7 (2017)
Martin-Herranz DE, Ribeiro AJM, Krueger F
Nucleic acids research
Yang J, Ryan DJ, Wang W
Kelsey G, Stegle O, Reik W
Science (New York, N.Y.)
358 1095-9203:69-75 (2017)
Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation.
Mohammed H, Hernando-Herraez I, Savino A
20 2211-1247:1215-1228 (2017)
Guo G, von Meyenn F, Rostovskaya M
Development (Cambridge, England)
144 1477-9129:2748-2763 (2017)
Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
Kirschner K, Chandra T, Kiselev V
19 2211-1247:1503-1511 (2017)
Vasiliauskaitė L, Vitsios D, Berrens RV
Nature structural & molecular biology
Stubbs TM, Bonder MJ, Stark AK
18 1474-760X:68 (2017)
Angermueller C, Lee HJ, Reik W
18 1474-760X:67 (2017)
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.
Hahn O, Grönke S, Stubbs TM
18 1474-760X:56 (2017)
Kiselev VY, Kirschner K, Schaub MT