Solenn PatalanoShort Biography
• 2011-current: Post-Doctoral Research Associate, Babraham Institute, Cambridge. (Funded by Wellcome Trust grant)
• 2009-2010: Research Assistant, Institute of Zoology, London (Funded by NERC grant)
• 2008: European PhD in Molecular, Cellular and Developmental Biology, CRG, Barcelona/ Nice. (Fellowship from Spanish Government, EUROBIO recognition for mobility and adaptability in new working environment)
Research Interests and Activities
“Sociogenomic” is a very recent but active field to study social organisation in molecular term. My current research seeks to understand the epigenetic mechanisms underlying genomic regulation and variability across individuals in the context of a social organisation.
My activities focus on the exploration of the dynamic of DNA methylation for the neuronal and behavioural plasticity. I am using two social insect models (the Polistes paper wasp and the Dinoponera Dinosaur ant). Social insects and particularly those organized into simple societies (with few individuals per colony) are interesting groups which retain some trait from their solitary ancestors like flexibility in reproduction behaviour. We are using this natural plasticity of insect societies, their ordinary range of behaviours and their genomes’ simplicity to investigate the mechanisms of the maintenance of phenotypic plasticity.
Vasiliauskaitė L, Berrens RV, Ivanova I
Nature structural & molecular biology
25 1545-9985:394-404 (2018)
Eckersley-Maslin MA, Alda-Catalinas C, Reik W
Nature reviews. Molecular cell biology
Guo G, von Meyenn F, Rostovskaya M
Development (Cambridge, England)
145 1477-9129: (2018)
Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data.
Olova N, Krueger F, Andrews S
19 1474-760X:33 (2018)
scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.
Clark SJ, Argelaguet R, Kapourani CA
9 2041-1723:781 (2018)
Regev A, Teichmann SA, Lander ES
6 2050-084X: (2017)
Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
Aarts M, Georgilis A, Beniazza M
Genes & development
An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.
Berrens RV, Andrews S, Spensberger D
Cell stem cell
21 1875-9777:694-703.e7 (2017)
Martin-Herranz DE, Ribeiro AJM, Krueger F
Nucleic acids research
Yang J, Ryan DJ, Wang W
Kelsey G, Stegle O, Reik W
Science (New York, N.Y.)
358 1095-9203:69-75 (2017)
Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation.
Mohammed H, Hernando-Herraez I, Savino A
20 2211-1247:1215-1228 (2017)