Life Sciences Research for Lifelong Health

Charlene Fabian

Charlene was awarded an MSci in Molecular and Cellular Biology by the University of Glasgow in 2016. As part of her course, Charlene undertook a one-year research placement within the Refractory, Respiratory and Inflammation Discover Performance Unit of GSK, where she was involved in target identification.

Charlene started her PhD at the Babraham Institute in October 2016 and is funded by an MRC Industrial CASE Studentship. In collaboration with DefiniGEN, Charlene will investigate the role of epigenetic processes in the specification of pancreatic cells from human pluripotent stem cells.

Latest Publications

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ

Cell systems
2405-4712: (2018)

PMID: 30031774

Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks.

Choy MK, Javierre BM, Williams SG

Nature communications
9 2041-1723:2526 (2018)

PMID: 29955040

Identifying Human Naïve Pluripotent Stem Cells - Evaluating State-Specific Reporter Lines and Cell-Surface Markers.

Collier AJ, Rugg-Gunn PJ

BioEssays : news and reviews in molecular, cellular and developmental biology
1521-1878:e1700239 (2018)

PMID: 29574793

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981

Derivation and Culture of Epiblast Stem Cell (EpiSC) Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)

PMID: 28049783