Life Sciences Research for Lifelong Health

Laetitia Chauve

Genetics and its interaction with the environment have always fascinated me. I studied biology at the University Pierre and Marie Curie and Ecole Normale Superieure in Paris, after which I did my first year of master internship in the Morimoto lab at Northwestern University. There I discovered the great model organism C. elegans and the beauty of in vivo monitoring of stress reporters. I did my second year of master internship in the Bessereau lab at Ecole Normale Superieure in Paris where I first came across the powerful genome-engineering tools based on the mobilization of the exogenous Mos1 transposon. During my PhD, I have been very interested in understanding why the stress transcription factor HSF-1 is essential for C. elegans development. I am very excited to have recently joined the Casanueva lab as a postdoc to investigate the basis for inter-individual variation in lifespan. Outside the lab, I enjoy playing listening to gipsy-jazz, playing bass guitar and bass recorder and salsa dancing.

01223 496102

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Latest Publications

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981

Derivation and Culture of Epiblast Stem Cell (EpiSC) Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093971 (2017)

PMID: 28049783

Derivation and Culture of Extra-Embryonic Endoderm Stem Cell Lines.

Rugg-Gunn P

Cold Spring Harbor protocols
2017 1559-6095:pdb.prot093963 (2017)

PMID: 28049782

Crosstalk between pluripotency factors and higher-order chromatin organization.

Lopes Novo C, Rugg-Gunn PJ

Nucleus (Austin, Tex.)
1949-1042:0 (2016)

PMID: 27759487

Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification.

von Meyenn F, Berrens RV, Andrews S

Developmental cell
39 1878-1551:104-115 (2016)

PMID: 27728778