Babraham Institute

Decidualisation and placentation defects are a major cause of age-related reproductive decline.

Woods L, Perez-Garcia V, Kieckbusch J

Nature communications
8 2041-1723:352 (2017)

PMID: 28874785

Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.

Turco MY, Gardner L, Hughes J

Nature cell biology
1476-4679: (2017)

PMID: 28394884

From the stem of the placental tree: trophoblast stem cells and their progeny.

Latos PA, Hemberger M

Development (Cambridge, England)
143 1477-9129:3650-3660 (2016)

PMID: 27802134

Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiation.

Murray A, Sienerth AR, Hemberger M

Scientific reports
6 2045-2322:25112 (2016)

PMID: 27121762

What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast.

Lee CQ, Gardner L, Turco M

Stem cell reports
6 2213-6711:257-72 (2016)

PMID: 26862703

Maternal DNA Methylation Regulates Early Trophoblast Development.

Branco MR, King M, Perez-Garcia V

Developmental cell
36 1878-1551:152-63 (2016)

PMID: 26812015

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

Latos PA, Sienerth AR, Murray A

Genes & development
1549-5477: (2015)

PMID: 26584622

Direct Induction of Trophoblast Stem Cells from Murine Fibroblasts.

Kubaczka C, Senner CE, Cierlitza M

Cell stem cell
17 1875-9777:557-68 (2015)

PMID: 26412560

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

Latos PA, Goncalves A, Oxley D

Nature communications
6 2041-1723:7776 (2015)

PMID: 26206133

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.

F Cambuli, A Murray, W Dean

Nat Commun.
26 5:5538 (2014)

PMID: 25423963

ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells.

Roper SJ, Chrysanthou S, Senner CE

Nucleic acids research
42 1362-4962:8914-27 (2014)

PMID: 25034692

Derivation and maintenance of murine trophoblast stem cells under defined conditions.

Kubaczka C,Senner C,Arauzo-Bravo MJ,Sharma N,Kuckenberg P,Becker A,Zimmer A,Brustle O,Peitz M, M Hemberger,Schorle H

Stem cell reports
2 2213-6711:232-42 (2014)

PMID: 24527396

Life Sciences Research for Lifelong Health