Babraham Institute

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells.

Koohy H, Bolland DJ, Matheson LS

Genome biology
19 1474-760X:126 (2018)

PMID: 30180872

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions.

Schoenfelder S, Javierre BM, Furlan-Magaril M

Journal of visualized experiments : JoVE
1940-087X: (2018)

PMID: 30010637

Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks.

Choy MK, Javierre BM, Williams SG

Nature communications
9 2041-1723:2526 (2018)

PMID: 29955040

The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia.

Beekman R, Chapaprieta V, Russiñol N

Nature medicine
1546-170X: (2018)

PMID: 29785028

Allele-specific control of replication timing and genome organization during development.

Rivera-Mulia JC, Dimond A, Vera D

Genome research
1549-5469: (2018)

PMID: 29735606

Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition.

Novo CL, Javierre BM, Cairns J

Cell reports
22 2211-1247:2615-2627 (2018)

PMID: 29514091

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures.

Comoglio F, Park HJ, Schoenfelder S

Genome research
1549-5469: (2018)

PMID: 29429976

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

Wutz G, Várnai C, Nagasaka K

The EMBO journal
1460-2075: (2017)

PMID: 29217591

Capturing Three-Dimensional Genome Organization in Individual Cells by Single-Cell Hi-C.

Nagano T, Wingett SW, Fraser P

Methods in molecular biology (Clifton, N.J.)
1654 1940-6029:79-97 (2017)

PMID: 28986784

Chromosome contacts in activated T cells identify autoimmune disease candidate genes.

Burren OS, Rubio García A, Javierre BM

Genome biology
18 1474-760X:165 (2017)

PMID: 28870212

Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.

Rubin AJ, Barajas BC, Furlan-Magaril M

Nature genetics
1546-1718: (2017)

PMID: 28805829

Platelet function is modified by common sequence variation in megakaryocyte super enhancers.

Petersen R, Lambourne JJ, Javierre BM

Nature communications
8 2041-1723:16058 (2017)

PMID: 28703137

Life Sciences Research for Lifelong Health