Life Sciences Research for Lifelong Health
Varga-Weisz Group members

Patrick Varga-Weisz

Patrick was born in Neustadt and der Weinstrasse, Southwest Germany, a town not far from Heidelberg and the French Border. His father was a Hungarian artist ( and his mother a wine chemist. This genetic background may have predestined Patrick to become a molecular biologist (who occasionally dabbles into studying yeast). Patrick did his undergraduate degree (‘Vordiplom’) at the University of Tubingen (1983-1986) in Biochemistry and his Ph.D. at Oregon State University (OSU) on Peptide Growth Inhibitors in the laboratory of David Barnes (a pioneer of the development of serum-free cell culture technology, now at Mount Desert Laboratory, Maine. Patrick then joined the laboratory of Ken van Holde, also at OSU and this brought him into the chromatin field. He continued his studies of chromatin at the EMBL as postdoc in the laboratory of Peter Becker, now Professor at Munich University. Patrick became a group leader at the Marie Curie Research Institute, Surrey, in 1997 and joined the Babraham Institute late in 2004. He is a member of the Epigenome Network of Excellence.

01223 496434

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Latest Publications

A SUV39H1-low chromatin state characterises and promotes migratory properties of cervical cancer cells.

Rodrigues C, Pattabiraman C, Vijaykumar A

Experimental cell research
1090-2422: (2019)

PMID: 30772380

Enzymatic Assays of Histone Decrotonylation on Recombinant Histones.

Fellows R, Varga-Weisz P

8 2331-8325: (2018)

PMID: 30283810

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases.

Fellows R, Denizot J, Stellato C

Nature communications
9 2041-1723:105 (2018)

PMID: 29317660

ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.

Sun H, Damez-Werno DM, Scobie KN

Nature medicine
1546-170X: (2015)

PMID: 26390241

A novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I.

Petrini E, Baillet V, Cridge J

Journal of cell science
1477-9137: (2015)

PMID: 26345368

Chromatin remodeling: a collaborative effort.

Varga-Weisz PD

Nature structural & molecular biology
21 1545-9985:14-6 (2014)

PMID: 24389547

Keeping chromatin quiet: how nucleosome remodeling restores heterochromatin after replication.

JE Mermoud, SP Rowbotham, PD Varga-Weisz

Cell cycle (Georgetown, Tex.)
10 23:4017-25 (2011)

DOI: 10.4161/cc.10.23.18558

PMID: 22101266

Insights into how chromatin remodeling factors find their target in the nucleus.

PD Varga-Weisz

Proceedings of the National Academy of Sciences of the United States of America
107 46:19611-2 (2010)

DOI: 10.1073/pnas.1014956107

PMID: 21059914

The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci.

A Neves-Costa, WR Will, AT Vetter

PloS one
4 12:e8111 (2009)

DOI: 10.1371/journal.pone.0008111

PMID: 19956593