Life Sciences Research for Lifelong Health

Myriam Hemberger

Myriam Hemberger studied at the University of Freiburg and Max-Planck Institute for Molecular Genetics, Berlin, Germany, (PhD) and trained as postdoctoral fellow (with funding from the Ernst Schering Research foundation and a long-term HFSP postdoctoral fellowship) at the Samuel Lunenfeld Research Institute in Toronto and at the University of Calgary, Canada.

Since 2004 she has been group leader at the Babraham Institute in Cambridge, UK, first as MRC Career Development Fellow and since 2009 on a tenured position as part of Babraham’s Epigenetics Programme. In 2007 she was awarded the IFPA Award in Placentology for her contributions to the field.

Her research interests are on molecular mechanisms of the genetic – epigenetic crosstalk that ensures formation of a functional placenta. Current project areas include the intersection between transcriptional networks and the epigenome that ensure the stem cell state of TS cells in the mouse and human placenta, and effect of physiological and environmental influences on the trophoblast’s epigenome and consequent differentiation deficits.

Myriam is now based at the University of Calgary

01223 496534

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Latest Publications

Mechanisms of early placental development in mouse and humans.

Hemberger M, Hanna CW, Dean W

Nature reviews. Genetics
1471-0064: (2019)

PMID: 31534202

ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains.

Shi H, Strogantsev R, Takahashi N

Epigenetics & chromatin
12 1756-8935:49 (2019)

PMID: 31399135

Common and distinct transcriptional signatures of mammalian embryonic lethality.

Collins JE, White RJ, Staudt N

Nature communications
10 2041-1723:2792 (2019)

PMID: 31243271

Inhibition of Phosphoinositide-3-Kinase Signaling Promotes the Stem Cell State of Trophoblast.

Lee CQE, Bailey A, Lopez-Tello J

Stem cells (Dayton, Ohio)
37 1549-4918:1307-1318 (2019)

PMID: 31233251

Regulation of Placental Development and Its Impact on Fetal Growth-New Insights From Mouse Models.

Woods L, Perez-Garcia V, Hemberger M

Frontiers in endocrinology
9 1664-2392:570 (2018)

PMID: 30319550

Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages.

Schoenfelder S, Mifsud B, Senner CE

Nature communications
9 2041-1723:4189 (2018)

PMID: 30305613

A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells.

Chrysanthou S, Senner CE, Woods L

Stem cell reports
2213-6711: (2018)

PMID: 29576538

Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta

Lee CQE, Turco M, Gardner L

Development (Cambridge, England)
1477-9129: (2018)

PMID: 29540503

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

Perez-Garcia V, Fineberg E, Wilson R

1476-4687: (2018)

PMID: 29539633