Life Sciences Research for Lifelong Health

Group Members

Dr Michael Coleman

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Dr Robert Adalbert

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Dr Jonathan Gilley

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Stacey Gould

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Miss Stacey Gould

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Dr Claire Harwell

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Dr Ciaran Hill

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Dr Andrea Loreto

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Dr Matthew White

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Mrs Nina Yang

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Latest Publications

Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.

Adalbert R, Milde S, Durrant C

Neurobiology of aging
68 1558-1497:68-75 (2018)

PMID: 29729423

TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.

White MA, Kim E, Duffy A

Nature neuroscience
1546-1726: (2018)

PMID: 29556029

Neuronal Cell Death.

Fricker M, Tolkovsky AM, Borutaite V

Physiological reviews
98 1522-1210:813-880 (2018)

PMID: 29488822

Sarm1 Deletion, but Not Wld(S), Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.

Gilley J, Ribchester RR, Coleman MP

Cell reports
21 2211-1247:10-16 (2017)

PMID: 28978465

NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.

Di Stefano M, Loreto A, Orsomando G

Current biology : CB
1879-0445: (2017)

PMID: 28262487

Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice.

Harwell CS, Coleman MP

Molecular neurodegeneration
11 1750-1326:44 (2016)

PMID: 27287430

Traumatic Axonal Injury: Mechanisms and Translational Opportunities.

Hill CS, Coleman MP, Menon DK

Trends in neurosciences
39 1878-108X:311-24 (2016)

PMID: 27040729

Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.

Gilley J, Ando K, Seereeram A

Neurobiology of aging
39 1558-1497:1-18 (2016)

PMID: 26923397

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.

Rodríguez-Martín T, Pooler AM, Lau DH

Neurobiology of disease
85 1095-953X:1-10 (2015)

PMID: 26459111