Life Sciences Research for Lifelong Health
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Krishnendu Chakraborty

Krish was awarded Ph.D. in Life Sciences from Jadavpur University, Kolkata, India in 2010. During his doctoral research he studied cancer mediated Immunosuppression and role of Neem leaf glycoprotein (NLGP) and Interferon alpha 2b as an immune modulator in the maintenance of immune homeostasis during head and neck squamous cell carcinoma (HNSCC). After finishing his doctoral thesis I joined Dept. of Pathobiological Sciences, Louisiana State University, USA and pursued his further research in the field of viral immunology. As a postdoctoral researcher he studied the role of immune modulatory cytokines in human metapneumo virus (hMPV) infection model. Presently he is working as a postdoctoral scientist in the Dept. of Lymphocyte Signalling Lab and Development, Babraham Institute, Cambridge, UK. His current interest is to determine the role of Phosphokinases and RNA binding proteins in Influenza virus infection.

Latest Publications

Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease.

Paz K, Flynn R, Du J

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
1600-6143: (2019)

PMID: 30748099

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA

Journal of immunology (Baltimore, Md. : 1950)
1550-6606: (2019)

PMID: 30692213

PI3K induces B-cell development and regulates B cell identity.

Abdelrasoul H, Werner M, Setz CS

Scientific reports
8 2045-2322:1327 (2018)

PMID: 29358580

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H

Immunity
47 1097-4180:875-889.e10 (2017)

PMID: 29166588

Multi-tissue DNA methylation age predictor in mouse.

Stubbs TM, Bonder MJ, Stark AK

Genome biology
18 1474-760X:68 (2017)

PMID: 28399939

Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy.

Okkenhaug K, Graupera M, Vanhaesebroeck B

Cancer discovery
2159-8290: (2016)

PMID: 27655435

Ionic immune suppression within the tumour microenvironment limits T cell effector function.

Eil R, Vodnala SK, Clever D

Nature
537 1476-4687:539-543 (2016)

PMID: 27626381