Life Sciences Research for Lifelong Health
lab photo hero

Daisy Luff

Daisy graduated from the University of Cambridge in 2014 with a BA and Master of Natural Sciences degree, specialising in biochemistry. Her early undergraduate research investigated the molecular basis of integrin binding to collagen in the lab of Professor R Farndale. In 2013 she undertook a summer studentship with Professor D Carling at the MRC CSC in London investigating the role of AMPK in prostate cancer. Her subsequent masters research focused on identifying LRRK2 binding partners in the lab of Professor N Gay at the Department of Biochemistry. Daisy's current research at the Babraham Institute aims to elucidate the molecular mechanisms underlying PI3K p110 isoform-specific roles in lymphocytes.

Latest Publications

Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease.

Paz K, Flynn R, Du J

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
1600-6143: (2019)

PMID: 30748099

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA

Journal of immunology (Baltimore, Md. : 1950)
1550-6606: (2019)

PMID: 30692213

PI3K induces B-cell development and regulates B cell identity.

Abdelrasoul H, Werner M, Setz CS

Scientific reports
8 2045-2322:1327 (2018)

PMID: 29358580

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis.

Kishore M, Cheung KCP, Fu H

Immunity
47 1097-4180:875-889.e10 (2017)

PMID: 29166588

Multi-tissue DNA methylation age predictor in mouse.

Stubbs TM, Bonder MJ, Stark AK

Genome biology
18 1474-760X:68 (2017)

PMID: 28399939

Targeting PI3K in Cancer: Impact on Tumor Cells, Their Protective Stroma, Angiogenesis, and Immunotherapy.

Okkenhaug K, Graupera M, Vanhaesebroeck B

Cancer discovery
2159-8290: (2016)

PMID: 27655435

Ionic immune suppression within the tumour microenvironment limits T cell effector function.

Eil R, Vodnala SK, Clever D

Nature
537 1476-4687:539-543 (2016)

PMID: 27626381