From Petri Dish To Human: Lost in Translation
In an increasingly competitive environment more and more life science research has to be translatable to the therapeutic or diagnostic arenas. The journey from Petri dish to human is a long one and fraught with pitfalls. Even the best ideas have an arduous journey if they are to make it to commercial application. Several high profile studies have recently called into question the reproducibility of life science research which at best undermines the reputation of a lab and at worst can lead to retracted papers and threatens future funding from both academic institutions and industrial collaborators. Additionally avoiding doomed in vivo experiments can save much time and money and has significant ethical benefits. Yet the risk of failure in vivo due to flawed in vitro experiments can be easily reduced by using current best practices and technologies. These range from simple, free to implement practices to the very latest cell biology tools. Such quality control practices and use of standards are commonplace in disciplines such as chemistry and engineering – life science is catching up. This seminar will help you get ahead of the curve.
About the speaker:
Nick Amiss studied biochemistry at Warwick University, England, graduating in 2001. He has gained extensive cell culture research experience in market leading companies including: biopharmaceutical process development at GSK using bioreactor culture of adherent human cells on microcarriers, researching preclinical drug development and culture process optimisation at AstraZeneca-MedImmune, developing novel therapeutics and luminescent cell lines for xenotransplantation at Antisoma & providing technical training & engineering support for bioreactors at Infors & Applikon.