What makes you, you? Why are some people more susceptible to diseases or infections than others?
It all begins with your DNA, your genome, a complete set of instructions and all the information needed to build and maintain you. Your DNA is a chemical sequence which is contained in chromosomes. Chromosomes are most commonly depicted as X-shaped ‘blobs’ found in the nucleus of a cell. However, researchers at the Babraham Institute developed a new technique which has allowed them to get a more accurate three dimensional picture of how the DNA folds within the chromosome. Your DNA is dynamic, constantly changing in shape – most of the time it’s not in the familiar X-shape.
But, why does it do this? Why is this important? Why do Babraham Institute researchers study it? Our genomes contain all our genes which influence, contribute to, or control nearly all aspects of our daily lives, from our health, well-being and longevity, to our aptitude for learning and our adaption and responses to diet, drugs and the environment. Our researchers have discovered that the way our genome folds plays a big role in turning genes on and off, deciding which genes are expressed, and by how much. We are trying to build an understanding of how chromosome structure and interactions between distant regions of the genome regulate genes and make us who we are.
To further explore their data, our researchers have been working with musician Max Cooper and visual artist Andy Lomas to turn their research into multidimensional art.
Join us for an exciting opportunity to climb inside the data! This adult-only event will take place at the Hidden Rooms, Cambridge and will include the chance to explore the data through Virtual Reality as well as a preview of the CHROMOS music and video, short talks from Institute researchers and a Q&A session chaired by Dr Kat Arney, author of 'Herding Hemingway's Cats - Understanding How Our Genes Work', Naked Scientists co-presenter, producer and presenter of Naked Genetics podcast.
Tickets cost £5 and include your first drink.
Booking is essential, please book here. (Booking opens on Monday 20th February).
The Babraham Institute is supporting a number of other events at the Cambridge Science Festival, please follow the links below to find out more:
Wednesday 15th March: Mini-me: How 3D Organoids are revolutionising research
Tuesday 21st March (6pm - 8pm): Epigenetics: DNA Does Not Account for everything
Saturday 18th & Sunday 19th March (all day): Babraham Institute Molecular Explorer's at The Guildhall
Thursday 23rd March (6.30pm - 8pm): In Conversation with the Babraham Institute
The Hidden Rooms, Cambridge