Research

Research summaries from our 2019-2020 Annual Research Report

This video is an annual summary of our PI3K and signalling research from the labs of Len Stephens and Phill Hawkins.

Read more about our signalling research and why it is important on our research pages.

Read more about the research in Len and Phill's lab on their group pages.

This video is an annual summary of our epigenetics research from the lab of Stefan Schoenfelder.

Read more about our epigenetics research and why it is important on our research pages.

Read more about Stefan's group's research on the group's page.

This video is an annual summary of our immunology research from the lab of Michelle Linterman.

Read more about our immunology research and why it is important on our research pages.

Read more about the Linterman lab's research on the group's page.

Elena and Rinako present: MicroRNA-155 controls affinity-based selection by protecting c-MYC+ B cells from apoptosis

This is a video summary presenting new findings published in The Journal of Clinical Investigation about the role of microRNA-155 in the affinity-based selection of B cells. Two of the paper’s authors, Rinako Nakagawa and Elena Vigorito, provide a personally guided tour of their results. The results of this study may extend our understanding of the pathogenesis of lymphomas and open up new therapeutic targets.

News link: A testing time: understanding more about how the ‘best’ B cells are selected

Keywords: Research, immunology, B cells, apoptosis, antibodies, germinal centre, microRNA-155, c-Myc

Date: December 2015

The inner galaxy of your genes

A video by researchers at the Babraham Institute allows a glimpse into the physical interactions occurring in the genome. Reflecting the beauty of a distant galaxy, the video shows a three-dimensional view of the contact points between the 22,000 genes in the mouse genome.

News link: Come here and be quiet!

Keywords: genome, genes, polycomb proteins, nuclear dynamics

Date: November 2015

T cells on surveillance

The video clip shows memory T cells (green) actively patrolling the skin surface (blue) in case of re-infection with a similar pathogen. Find more videos like this on our Weapons of Microscopic Destruction website, plus games and more information on how the immune system works.

Date: May 2015

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with.

News item: ‘X-shape’ not true picture of chromosome structure, new imaging technique reveals

Keywords: chromosome, shape, DNA, folding, genes, nuclear dynamics

Date: September 2013

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