Life Sciences Research for Lifelong Health

Mini-me: How 3D organoids are revolutionising research


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Babraham Institute scientists Joerg Stange, Barzan Sadiq, Joana Guedes and Marisa Stebegg joined colleagues from the Cambridge Stem Cell Institute; Wellcome Genome Campus and the Gurdon Institute at Murray Edwards College, Cambridge, on Wednesday 15th March.

An organoid is a 3D multicellular in vitro tissue construct that mimics its corresponding in vivo organ, so that it can be used to study aspects of that organ in a tissue culture dish. The panel discussed why this technology so important for biomedical research and addressed questions from the audience which showed the high level of interest in how advances in the technology could affect us all in the future.

"Which are the main applications for those organoids?Which are the most common organoids that scientists are able to develop?"

"Is it possible to grow organs of the size, appropriate to then be transplanted into a human body as a transplant?"

"What are the main challenges in translating basic research on organoids into widely available clinical interventions?"




Photographs by Chris Loades © Babraham Institute 2017