Babraham Institute Theses 2009

(University of Cambridge unless otherwise stated)

Arkell RS Investigations into the regulation of DUSP6 expression in normal and tumour cells.

Burman C The identification and characterisation of aminergic G-protein coupled receptors from Amphioxus.

Chessa TAM Novel insights into the mechanism of assembly and activation of the neutrophil NADPH oxidase.

Chotalia M Investigating the role of transcription events in establishing methylation imprint marks at the Gnas locus.

Choudhary P Interaction of REST with ATAD2 promotes neuronal gene expression.

Drozd AC Mechanisms of insulin-like growth factor binding protein-5 (IGFBP-5) action during myogenesis.

Gomez de la Cuesta Laporta, R Mechanism of regulation of the Ras-GTPase activating protein CAPRI.

Higazi DR Calcium, endothelin and inositol 1,4,5-trisphosphate; a complex interplay in the regulation of myocardial hypertrophy.

Jagadesham V Characterisation of V-D intergenic DNase hypersensitive sites in the immunoglobulin heavy chain locus.

Knights AJ Expression studies on F59D12.1, an orphan G protein-coupled receptor from Caenorhabditis elegans.

McNee GS p38 MAP kinase regulated PLD1 activity controls stress-induced EGF receptor internalisation.

Milne L PtdIns(3,4,5)P3 distribution during neutrophil chemotaxis.

Paxton CW Kelch related protein 1 in myogenesis.

Ramadani F The role of class IA catalytic PI3K isoforms in lymphocyte development and function.

Shivji N GnRH neuron migration during embryonic development.

Soond DR Control of effector and memory T cells by the PI3K/Pten pathway.

Tudor S Attempts to isolate omegasomes - the platform for autophagosome biogenesis.

Wiggins CM The role of phosphorylation and ubiquitination in the degradation of the pro-apoptotic protein BimEL.

Wilbrey AL Sub-nuclear targeting of the WldS protein and the role of the NAD+ synthesis in delaying Wallerian degeneration.