The Babraham Institute receives strategic funding from the BBSRC
The Babraham Institute receives strategic funding from the BBSRC
Refereed Journals
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
Theses
Key Publications
Institute Publications
(Babraham Institute Authors are listed in bold type)
Adalbert R, Gilley J, Coleman MP (2007) Aβ, tau and ApoE4 in Alzheimer's disease: the axonal connection.
Trends in Molecular Medicine 13 135-142
http://dx.doi.org/10.1016/j.molmed.2007.02.004
Al-Alwan MM, Okkenhaug K, Vanhaesebroeck B, Hayflick JS, Marshall AJ (2007) Requirement for phosphoinositide 3-kinase p110δ signaling in B cell antigen receptor-mediated antigen presentation.
Journal of Immunology 178 2328-2335
http://www.jimmunol.org/cgi/content/full/178/4/2328
Andrews S, Stephens LR, Hawkins PT (2007) PI3K class IB pathway.
Science STKE cm2
http://dx.doi.org/10.1126/stke.4072007cm2
Andrews S, Stephens LR, Hawkins PT (2007) PI3K class IB pathway in neutrophils.
Science STKE cm3
http://dx.doi.org/10.1126/stke.4072007cm3
Barber MA, Donald S, Thelen S, Anderson KE, Thelen M, Welch HCE (2007) Membrane translocation of P-Rex1 is mediated by G protein βγ subunits and phosphoinositide 3-kinase.
Journal of Biological Chemistry 282 29967-29976
http://dx.doi.org/10.1074/jbc.M701877200
Bellamy TC (2007) Presynaptic modulation of parallel fibre signalling to Bergmann glia.
Neuropharmacology 52 368-375
http://dx.doi.org/10.1016/j.neuropharm.2006.08.009
Bello D, Aslam T, Bultynck G, Slawin AMZ, Roderick HL, Bootman MD, Conway SJ (2007) Synthesis and biological action of novel 4-position-modified derivatives of [SMALL CAP]D[small cap]-myo-inositol 1,4,5-trisphosphate.
Journal of Organic Chemistry 72 5647-5659
http://dx.doi.org/10.1021/jo070611a
Berridge MJ (2007) Inositol trisphospate and calcium oscillations.
Biochemical Society Symposia 74 1-7
http://symposia.biochemistry.org/bssymp/074/bss0740001.htm
Bolland D, Corcoran AE (2007) Somatic hypermutation is a matter of choice.
Nature Immunology 8 677-679
http://dx.doi.org/10.1038/ni0707-677
Bolland DJ, Wood AL, Afshar R, Featherstone K, Oltz EM, Corcoran AE (2007) Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer, Eμ.
Molecular and Cellular Biology 27 5523-5533
http://dx.doi.org/10.1128/MCB.02407-06
Bootman MD, Harzheim D, Smyrnias I, Conway SJ, Roderick HL (2007) Temporal changes in atrial EC-coupling during prolonged stimulation with endothelin-1.
Cell Calcium 42 489-501
http://dx.doi.org/j.ceca.2007.05.004
Brooks WM, Lynch PJ, Ingle CC, Hatton A, Emson PC, Faull RL, Starkey MP (2007) Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease.
Brain Research 1127 127-135
http://dx.doi.org/10.1016/j.brainres.2006.09.106
Bruckbauer A, James PS, Zhou D, Yoon JW, Excell D, Korchev Y, Jones R, Klenerman D (2007) Nanopipette delivery of individual molecules to cellular compartments for single-molecule fluorescence tracking.
Biophysical Journal 93 3120-3131
http://dx.doi.org/10.1529/biophysj.107.104737
Burman C, Maqueira B, Coadwell WJ, Evans PD (2007) Eleven new putative aminergic G-protein coupled receptors from Amphioxus (Branchiostoma floridae): identification, sequence analysis and phylogenetic relationship.
Invertebrate Neuroscience 7 87-98
http://dx.doi.org/10.1007/s10158-006-0041-z
Carter C, Dion C, Schnell S, Coadwell WJ, Graham M, Hepburn L, Morgan G, Hutchings A, Pascall JC, Jacobs H, Miller JR, Butcher GW (2007) A natural hypomorphic variant of the apoptosis regulator Gimap4/IAN1.
Journal of Immunology 179 1784-1795
http://www.jimmunol.org/cgi/content/full/179/3/1784
Caudle WM, Richardson JR, Wang MZ, Taylor TN, Guillot TS, McCormack AL, Colebrooke RE, Di Monte DA, Emson PC, Miller GW (2007) Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration.
Journal of Neuroscience 27 8138-8148
http://dx.doi.org/10.1523/JNEUROSCI.0319-07.2007
Chalmers CJ, Gilley R, March HN, Balmanno K, Cook SJ (2007) The duration of ERK1/2 activity determines the activation of c-Fos and Fra-1 and the composition and quantitative transcriptional output of AP-1.
Cellular Signalling 19 695-704
http://dx.doi.org/10.1016/j.cellsig.2006.09.001
Chen G, Dimitriou ID, La Rose J, Ilangumaran S, Yeh W-C, Doody G, Turner M, Gommerman J, Rottapel R (2007) The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response.
Molecular and Cellular Biology 27 3109-3122
http://dx.doi.org/10.1128/MCB.01014-06
Clapp J, Mitchell LM, Bolland DJ, Fantes J, Corcoran AE, Scotting PJ, Armour JAL, Hewitt JE (2007) Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.
American Journal of Human Genetics 81 264-279
http://dx.doi.org/10.1086/519311
Colebrooke RE, Chan PM, Lynch PJ, Mooslehner K, Emson PC (2007) Differential gene expression in the striatum of mice with very low expression of the vesicular monoamine transporter type 2 gene.
Brain Research 1152 10-16
http://dx.doi.org/10.1016/j.brainres.2007.03.032
Colucci F (2007) Unexpected partnership between IL-15 and DAP10.
Nature Immunology 8 1289-1291
http://dx.doi.org/10.1038/ni1207-1289
Conforti L, Adalbert R, Coleman MP (2007) Neuronal death: where does the end begin?.
Trends in Neurosciences 30 159-166
http://dx.doi.org/10.1016/j.tins.2007.02.004
Conforti L, Fang G, Beirowski B, Wang MS, Sorci L, Asress S, Adalbert R, Silva A, Bridge K, Huang XP, Magni G, Glass JD, Coleman MP (2007) NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration.
Cell Death and Differentiation 14 116-127
http://dx.doi.org/10.1038/sj.cdd.4401944
Cook SJ, Morley SJ (2007) Nutrient-responsive mTOR signalling grows on Sterile ground.
Biochemical Journal 403 e1-e3
http://dx.doi.org/10.1042/BJ20070207 (Available only in electronic format)
Corcos D (2007) Ligand-independent activity of the B cell antigen receptor in physiology and pathology.
Archivum Immunologiae et Therapiae Experimentalis 55 77-82
http://dx.doi.org/10.1007/s00005-007-0010-1
Daly J, Licence ST, Nanou A, Morgan G, Martensson I-L (2007) Transcription of productive and nonproductive VDJ-recombined alleles after IgH allelic exclusion.
EMBO Journal 26 4273-4282
http://dx.doi.org/10.1038/sj.emboj.7601846
Davies W, Humby T, Isles AR, Burgoyne PS, Wilkinson LS (2007) X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder.
Biological Psychiatry 61 1351-1360
http://dx.doi.org/10.1016/j.biopsych.2006.08.011
Dear DV, Young DS, Kazlauskaite J, Meersman F, Oxley D, Webster J, Pinheiro TJT, Gill AC, Bronstein I, Lowe CR (2007) Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro.
Biochimica et Biophysica Acta - Proteins and Proteomics 1744 792-802
http://dx.doi.org/10.1016/j.bbapap.2007.05.005
Duquerroy S, Stura EA, Bressanelli S, Fabiane SM, Vaney MC, Beale D, Hamon M, Casali P, Rey FA, Sutton BJ, Taussig MJ (2007) Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.
Journal of Molecular Biology 368 1321-1331
http://dx.doi.org/10.1016/j.jmb.2007.02.085
Ewings KE, Hadfield-Moorhouse K, Wiggins CM, Wickenden JA, Balmanno K, Gilley R, Degenhardt K, White E, Cook SJ (2007) ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.
EMBO Journal 26 2856-2867
http://dx.doi.org/10.1038/sj.emboj.7601723
Ewings KE, Wiggins CM, Cook SJ (2007) Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels.
Cell Cycle 6 2236-2240
http://www.landesbioscience.com/journals/cc/article/4728
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins PT, Stephens LR (2007) PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis.
Nature Cell Biology 9 86-91
http://dx.doi.org/10.1038/ncb1517
Forsdike RA, Hardy K, Bull L, Stark J, Webber LJ, Stubbs S, Robinson JE, Franks S (2007) Disordered follicle development in ovaries of prenatally androgenized ewes.
Journal of Endocrinology 192 421-428
http://dx.doi.org/10.1677/joe.107097
Fraser P, Bickmore W (2007) Nuclear organization of the genome and the potential for gene regulation.
Nature 447 413-417
http://dx.doi.org/10.1038/nature05916
Gaboriau D, Howes EA, Clark J, Jones R (2007) Binding of sperm proacrosin/β-acrosin to zona pellucida glycoproteins is sulfate and stereodependent.
Synthesis of a novel fertilization inhibitor.
Developmental Biology 306 646-657
http://dx.doi.org/10.1016/j.ydbio.2007.04.001
Green K, Lewis AJ, Dawson C, Dean WL, Reinhart B, Chaillet JR, Reik W (2007) A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA.
Mammalian Genome 18 32-42
http://dx.doi.org/10.1007/s00335-006-0092-9
Guillou H, Lecureuil C, Anderson KE, Suire S, Ferguson GJ, Ellson CD, Gray A, Divecha N, Hawkins PT, Stephens LR (2007) Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns (3,4,5)P3 through a protein-lipid overlay approach.
Journal of Lipid Research 48 726-732
http://dx.doi.org/10.1194/jlr.D600038-JLR200
Hawkins PT, Davidson K, Stephens LR (2007) The role of PI3Ks in the regulation of the neutrophil NADPH oxidase.
Biochemical Society Symposia 74 59-67
http://symposia.biochemistry.org/bssymp/074/bss0740059.htm
Hawkins PT, Stephens LR (2007) PI3Kγ is a key regulator of inflammatory responses and cardiovascular homeostasis.
Science 318 64-66
http://dx.doi.org/10.1126/science.1145420
He M (2007) Going from DNA sequence to protein arrays.
BIOforum Europe 11 32-34
http://www.emagazinebioforum.com/bio/
He M, Taussig MJ (2007) Eukaryotic ribosmome display with in situ DNA recovery.
Nature Methods 4 281-288
http://dx.doi.org/10.1038/nmeth1001
He M, Taussig MJ (2007) Rapid discovery of protein interactions by cell-free protein technologies.
Biochemical Society Transactions 35 962-965
http://dx.doi.org/10.1042/BST0350962
He M, Wang M-W (2007) Arraying proteins by cell-free synthesis.
Biomolecular Engineering 24 375-380
http://dx.doi.org/10.1016/j.bioeng.2007.05.002
Hemberger M (2007) Epigenetic landscape required for placental development.
Cellular and Molecular Life Sciences 64 2422-2436
http://dx.doi.org/10.1007/S00018-007-7113-z
Hemberger M, Dean WL (2007) Epigenetic arbitration of cell fate decisions: tipping the bias.
Developmental Cell 12 176-178
http://dx.doi.org/j.devcel.2006.12.004
Higashi S, Biskup S, West AB, Trinkhaus D, Dawson VL, Faull RLM, Waldvogel HJ, Arai H, Dawson TM, Moore DJ, Emson PC (2007) Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.
Brain Research 1155 208-219
http://dx.doi.org/10.1016/j.brainres.2007.04.034
Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC (2007) Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.
Journal of Neurochemistry 100 368-381
http://dx.doi.org/10.1111/j.1471-4159.2006.04246.x
Hogan C, Varga-Weisz P (2007) The regulation of ATP-dependent nucleosome remodelling factors.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 618 41-51
http://dx.doi.org/doi:10.1016/j.mrfmmm.2006.07.010
Holmes AM, Roderick HL, McDonald F, Bootman MD (2007) Interaction between store-operated and arachidonate-activated calcium entry.
Cell Calcium 41 1-12
http://dx.doi.org/10.1016/j.ceca.2006.04.005
Horton PM, Nicol AU, Kendrick KM, Feng JF (2007) Spike sorting based upon machine learning algorithms (SOMA).
Journal of Neuroscience Methods 160 52-68
http://dx.doi.org/10.1016/j.jneumeth.2006.08.013
Ji H, Rintelen F, Waltzinger C, Meier DB, Bilancio A, Pearce W, Hirsch E, Wymman MP, Ruckle T, Camps M, Vanhaesebroeck B, Okkenhaug K, Rommel C (2007) Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation.
Blood 110 2940-2947
http://dx.doi.org/10.1182/blood-2007-04-086751
Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, Thompson CB (2007) The proapoptotic factors Bax and Bak regulate T cell proliferation through control of endoplasmic reticulum Ca2+ homeostasis.
Immunity 27 268-280
http://dx.doi.org/10.1016/j.immuni.2007.05.023
Kendrick KM (2007) Quality of life and the evolution of the brain.
Animal Welfare 16 Supplement 9-15
http://www.ingentaconnect.com/content/ufaw/aw/2007/00000016/A00102s1/art00003
Kim N, Saudemont A, Webb L, Camps M, Ruckle T, Hirsch E, Turner M, Colucci F (2007) The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion.
Blood 110 3202-3208
http://dx.doi.org/10.1182/blood-2007-02-075366
Kulkarni S, Woollard KJ, Thomas S, Oxley D, Jackson SP (2007) Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading.
Blood 110 1879-1886
http://dx.doi.org/10.1182/blood-2006-08-040980
Lambourne SL, Humby T, Isles AR, Emson PC, Spillantini MG, Wilkinson LS (2007) Impairments in impulse control in mice transgenic for the human FTPD-17 tauV337M mutation are exacerbated by age.
Human Molecular Genetics 16 1708-1719
http://dx.doi.org/10.1093/hmg/ddm119
Llorian M, Stamataki Z, Hill S, Turner M, Martensson I-L (2007) The P13K p110δ is required for down-regulation of RAG expression in immature B cells.
Journal of Immunology 178 1981-1985
http://www.jimmunol.org/cgi/content/abstract/178/4/1981
Marelli-Berg FM, Okkenhaug K, Mirenda V (2007) A two-signal model for T cell trafficking.
Trends in Immunology 28 267-273
http://dx.doi.org/10.1016/j.it.2007.04.008
Martensson I-L, Keenan RA, Licence ST (2007) The pre-B-cell receptor.
Current Opinion in Immunology 19 137-142
http://dx.doi.org/10.1016/j.coi.2007.02.006
McNeill E, Conway SJ, Roderick HL, Bootman MD, Hogg N (2007) Defective chemoattractant-induced calcium signalling in S100A9 null neutrophils.
Cell Calcium 41 107-121
http://dx.doi.org/10.1016/j.ceca.2006.05.004
McNeill L, Salmond RJ, Cooper JC, Carret CK, Cassady-Cain RL, Roche-Molina M, Tandon P, Holmes N, Alexander DR (2007) The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
Immunity 27 425-437
http://dx.doi.org/10.1016/j.immuni.2007.07.015
Miles J, Mitchell JA, Chakalova L, Goyenechea B, Osborne CS, O'Neill L, Tanimoto K, Engle JD, Fraser P (2007) Intergenic transcription, cell-cycle and the developmentally regulated epigenetic profile of the human beta-globin locus.
PLoS One 2 e630, [1-12]
http://dx.doi.org/10.1371/journal.pone.0000630 (Online only)
Mirenda V, Jarmin SJ, David R, Dyson J, Scott D, Gu Y, Lechler RI, Okkenhaug K, Marelli-Berg FM (2007) Physiologic and aberrant regulation of memory T cell trafficking by the costimulatory molecular CD28.
Blood 109 2968-2977
http://dx.doi.org/10.1182/blood-2006-10-050724
Nashed BF, Zhang T, Al-Alwan MM, Srinivasan G, Halayko AJ, Okkenhaug K, Vanhaesebroeck B, HayGlass KT, Marshall AJ (2007) Role of the phosphoinositide 3-kinase p110δ in generation of type 2 cytokine responses and allergic airway inflammation.
European Journal of Immunology 37 416-424
http://dx.doi.org/10.1002/eji.200636401
Okkenhaug K, Ali K, Vanhaesebroeck B (2007) Antigen receptor signalling: a distinctive role for the p110δ isoform of PI3K.
Trends in Immunology 28 80/87
http://dx.doi.org/10.1016/j.it.2006.12.007
Osborn MJ, Miller JR (2007) Rescuing yeast mutants with human genes.
Briefings in Functional Genomics and Proteomics 6 104-111
http://dx.doi.org/10.1093/bfgp/elm017
Osborne CS, Chakalova L, Mitchell JA, Horton AM, Wood AL, Bolland DJ, Corcoran AE, Fraser P (2007) Myc dynamically and preferentially relocates to a transcription factory occupied by Igh.
PLoS Biology 5 e192, 1763-1772
http://dx.doi.org/10.1371/journal.pbio.0050192
Ozanne SE, Constancia M (2007) Mechanisms of disease: the developmental origins of disease and the role of the epigenotype.
Nature Clinical Practice Endocrinology and Metabolism 3 539-546
http://dx.doi.org/10.1038/ncpendmet0531
Paranavitane V, Stephens LR, Hawkins PT (2007) Structural determinants of LL5β subcellular localisation and association with filamin C.
Cellular Signalling 19 817-824
http://dx.doi.org/10.1016/j.cellsig.2006.10.007
Patton DT, Garcon F, Okkenhaug K (2007) The PI3K p110δ controls T cell development, differentiation and regulation.
Biochemical Society Transactions 35 167-171
http://www.biochemsoctrans.org/bst/035/bst0350167.htm
Pearce AC, McCarty OJT, Calaminus SDJ, Vigorito E, Turner M, Watson SP (2007) Vav family proteins are required for optimal regulation of PLCγ2 by integrin αIIbβ3.
Biochemical Journal 401 753-761
http://dx.doi.org/10.1042/BJ20061508
Probst AV, Santos F, Reik W, Almouzni G, Dean WL (2007) Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote.
Chromosoma 116 403-415
http://dx.doi.org/10.1007/s00412-007-0106-8
Quilter CR, Blott SC, Wilson AE, Bagga MR, Sargent CA, Oliver GL, Southwood OI, Gilbert CL, Mileham A, Affara NA (2007) Porcine maternal infanticide as a model for puerperal psychosis.
American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144B 862-868
http://dx.doi.org/10.1002/ajmg.b.30529
Raaijmakers JH, Deneubourg L, Rehmann H, de Koning J, Zhang Z, Krugmann S, Erneux C, Bos JL (2007) The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner.
Cellular Signalling 19 1249-1257
http://dx.doi.org/10.1016/j.cellsig.2006.12.015
Reik W (2007) Stability and flexibility of epigenetic gene regulation in mammalian development.
Nature 447 425-432
http://dx.doi.org/10.1038/nature05918
Rider DA, Havenith CEG, de Ridder R, Schuurman J, Favre C, Cooper JC, Walker S, Baadsgaard O, Marschner S, van de Winkel JGJ, Cambier J, Parren PWHI, Alexander DR (2007) A human CD4 monoclonal antibody for the treatment of T-cell lymphoma combines inhibition of T-cell signaling by a dual mechanism with potent Fc-dependent effector activity.
Cancer Research 67 9945-9953
http://dx.doi.org/10.1158/0008-5472.CAN-07-1148
Roderick HL, Bootman MD (2007) Pacemaking, arrhythmias, inotropy and hypertrophy; the many possible facets of InsP3 signalling in cardiac myocytes.
Journal of Physiology 581 883-884
http://dx.doi.org/10.1113/jphysiol.2007.133819
Roderick HL, Higazi DR, Smyrnias I, Fearnley C, Harzheim D, Bootman MD (2007) Calcium in the heart: when it's good, it's very very good, but when it's bad, it's horrid.
Biochemical Society Transactions 35 957-961
http://dx.doi.org/10.1042/BST0350957
Rodriguez A, Vigorito E, Clare S, Warren MV, Couttet P, Soond DA, Van Dongen S, Grocock RJ, Das PP, Miska EA, Vetrie D, Okkenhaug K, Enright AJ, Dougan G, Turner M, Bradley A (2007) Requirement of bic/microRNA-155 for normal immune function.
Science 316 608-611
http://dx.doi.org/10.1126/science.1139253
Ruf N, Bahring S, Galetzka D, Pliushch G, Luft FC, Nurnberg P, Haaf T, Kelsey GD, Zechner U (2007) Sequence-based bioinformatic prediction and QUASEP identify genomic imprinting of the KCNK9 potassium channel gene in mouse and human.
Human and Molecular Genetics 16 2591-2599
http://dx.doi.org/10.1093/hmg/ddm216
Saudemont A, Hamrouni A, Marchetti P, Liu J, Jouy N, Hetuin D, Colucci F, Quesnel B (2007) Dormant tumor cells develop cross-resistance to apoptosis induced by CTLs or imatinib mesylate, via methylation of supressor of cytokine signalling 1.
Cancer Research 67 4491-4498
http://dx.doi.org/10.1158/0008-5472.CAN-06-1627
Saudemont A, Okkenhaug K, Colucci F (2007) p110δ is required for innate immunity to transplantable lymphomas.
Biochemical Society Transactions 35 183-185
http://www.biochemsoctrans.org/bst/035/bst0350183.htm
Schoenfelder S, Smits G, Fraser P, Reik W, Paro R (2007) Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila.
EMBO Reports 8 1068-1073
http://dx.doi.org/10.1038/sj.embor.7401094
Sexton T, Schober H, Fraser P, Gasser SM (2007) Gene regulation through nuclear organization.
Nature Structual and Molecular Biology 14 1049-1055
http://dx.doi.org/10.1038/nsmb1324
Sexton T, Umlauf D, Kurukuti S, Fraser P (2007) The role of transcription factories in large-scale structure and dynamics of interphase chromatin.
Seminars in Cell and Developmental Biology 18 691-697
http://dx.doi.org/10.1016/j.semcdb.2007.08.008
Stoevesandt O, Taussig MJ (2007) Affinity reagent resources for human proteome detection: initiatives and perspectives.
Proteomics 7 2738-2750
http://dx.doi.org/10.1002/pmic.200700155
Sutton KM, Hayat S, Chau N-M, Cook SJ, Pouyssegur J, Ahmed A, Perusinghe N, Le Floch R, Yang J, Ashcroft M (2007) Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.
Oncogene 26 3920-3929
http://dx.doi.org/10.1038/sj.onc.1210168
Taussig MJ, Stoevesandt O, Borrebaeck CAK, Bradbury AR, Cahill D, Cambillau C, de Daruvar A, Dubel S, Eichler J, Frank R, Gibson TJ, Gloriam D, Gold L, Herberg FW, Hermjakob H, Hoheisel JD, Joos TO, Kallioniemi O, Koegll M, Konthur Z, Korn B, Kremmer E, Krobitsch S, Landegren U, van der Maarel S, McCafferty J, Muyldermans S, Nygren P-A, Palcy S, Pluckthun A, Polic B, Przybylski M, Saviranta P, Sawyer A, Sherman DJ, Skerra A, Templin M, Ueffing M, Uhlen M (2007) ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome.
Nature Methods 4 13-17
http://dx.doi.org/10.1038/nmeth0107-13
Taylor JA, Goubillon M-L, Broad KD, Robinson JE (2007) Steroid control of gonadotropin-releasing hormone secretion: associated changes in pro-opiomelanocortin and preproenkephalin messenger RNA expression in the ovine hypothalamus.
Biology of Reproduction 76 524-531
http://dx.doi.org/10.1095/biolreprod.106.055533
Taylor SRJ, Alexander DR, Cooper JC, Higgins CF, Elliott JI (2007) Regulatory T cells are resistant to apoptosis via TCR but not P2X7.
Journal of Immunology 178 3474-3482
http://www.jimmunol.org/cgi/content/full/178/6/3474
Trabace L, Kendrick KM, Castrignano S, Colaianna M, De Giorgi A, Schiavone S, Lanni C, Cuomo V, Govoni S (2007) Soluble amyloid beta1-42 reduces dopamine levels in rat prefrontal cortex: relationship to nitric oxide.
Neuroscience 147 652-663
http://dx.doi.org/10.1016/j.neuroscience.2007.04.056
Trivedi D, Padinjat R (2007) RdgB proteins: functions in lipid homeostasis and signal transduction.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1771 692-699
http://dx.doi.org/10.1016/j.bbalip.2007.04.014
Turner SD, Yeung D, Hadfield K, Cook SJ, Alexander DR (2007) The NPM-ALK tyrosine kinase mimics TCR signalling pathways, inducing NFAT and AP-1 by Ras-dependent mechanisms.
Cellular Signalling 19 740-747
http://dx.doi.org/10.1016/j.cellsig.2006.09.007
Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, Kohlhaas S, Das PP, Miska EA, Rodriguez A, Bradley A, Smith KGC, Rada C, Enright AJ, Toellner K-M, MacLennan ICM, Turner M (2007) microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.
Immunity 27 847-859
http://dx.doi.org/10.1016/j.immuni.2007.10.009
Walters E (2007) Some observations on the correlation determinant.
Communications in Statistics - Simulation and Computation 36 1347-1354
http://dx.doi.org/10.1080/03610910601161280
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Babraham Institute - Babraham Research Campus - Cambridge - United Kingdom