Babraham Institute Publications in Refereed Journals 2004

(Babraham Institute Authors are listed in bold type)

Abraham IM, Todman MG, Korach KS, Herbison AE (2004) Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain.
Endocrinology 145 3055-3061
http://dx.doi.org/10.1210/en.2003-1676

Alexander DR (2004) Oncogenic tyrosine kinases, DNA repair and survival: the role of Bcl-XL deamidation in transformation and genotoxic therapies.
Cell Cycle 3 584-587
http://www.landesbioscience.com/journals/cc/article/alexanderCC3-5.pdf

Antoniou AN, Ford S, Taurog JD, Butcher GW, Powis SJ (2004) Formation of HLA-B27 homodimers and their relationship to assembly kinetics.
Journal of Biological Chemistry 279 8895-8902
http://dx.doi.org/10.1074/jbc.M311757200

Axe D (2004) Estimating the prevalence of protein sequences adopting functional enzyme folds.
Journal of Molecular Biology 341 1295-1315
http://dx.doi.org/10.1016/j.jmb.2004.06.058

Baba H, Suzuki T, Arai H, Emson PC (2004) Expression of nNOS and soluble guanylate cyclase in schizophrenic brain.
NeuroReport 15 677-680
http://www.neuroreport.com/pt/re/neuroreport/abstract.00001756-200403220-00020.htm

Balasubramaniam R, Chawla S, Mackenzie L, Schwiening CJ, Grace AA, Huang CL-H (2004) Nifedipine and diltiazem supress ventricular arrhythmogenesis and calcium release in mouse hearts.
Pflugers Archiv - European Journal of Physiology 449 150-158
http://dx.doi.org/10.1007/s00424-004-1321-2

Ball M, McLellan A, Collins B, Coadwell WJ, Stewart F, Moore T (2004) An abundant placental transcript containing an IAP-LTR is allelic to mouse pregnancy-specific glycoprotein 23 (Psg23): cloning and genetic analysis.
Gene 325 103-113
http://dx.doi.org/10.1016/j.gene.2003.10.001

Barrow AD, Astoul E, Floto A, Brooke G, Relou IAM, Jennings NS, Smith KGC, Ouwehand W, Farndale RW, Alexander DR, Trowsdale J (2004) Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2.
Journal of Immunology 172 5838-5842
http://www.jimmunol.org/cgi/content/abstract/172/10/5838

Bell SE, Vigorito E, McAdam S, Reynolds HM, Caraux A, Colucci F, Turner M (2004) PLCγ2 regulates Bcl-2 levels and is required for survival rather than differentiation of marginal zone and follicular B cells.
European Journal of Immunology 34 2237-2247
http://dx.doi.org/10.1002/eji.200425054

Berridge MJ (2004) Calcium signal transduction and cellular control mechanisms.
Biochimica et Biophysica Acta - Molecular Cell Research 1742 3-7
http://dx.doi.org/10.1016/j.bbamcr.2004.08.012

Blatner NR, Stahelin RV, Diraviyam K, Hawkins PT, Hong W, Murray D, Cho W (2004) The molecular basis of the differential subcellular localization of FYVE domains.
Journal of Biological Chemistry 279 53818-53827
http://dx.doi.org/10.1074/jbc.M408408200

Bolland DJ, Wood AL, Johnston CM, Bunting SF, Morgan G, Chakalova L, Fraser P, Corcoran AE (2004) Antisense intergenic transcription in V(D)J recombination.
Nature Immunology 5 630-637
http://dx.doi.org/10.1038/ni1068

Brown D, Stephens EA, Smith RG, Li G, Leng G (2004) Estimation of parameters for a mathematical model of growth hormone secretion.
Journal of Neuroendocrinology 16 936-946
http://dx.doi.org/10.1111/j.1365-2826.2004.01252.x

Cadwallader KA, Uddin M, Condliffe AM, Cowburn AS, White JF, Skepper JN, Ktistakis NT, Chilvers ER (2004) Effect of priming on activation and localization of phospholipase D-1 in human neutrophils.
European Journal of Biochemistry 271 2755-2764
http://dx.doi.org/10.1111/j.1432-1033.2004.04204.x

Casini G, Dal Monte M, Petrucci C, Gambellini G, Grouselle D, Allen JP, Kreienkamp H-J, Richter D, Epelbaum J, Bagnoli P (2004) Altered morphology of rod bipolar cell axonal terminals in the retinas of mice carrying genetic deletion of somatostatin subtype receptor 1 or 2.
European Journal of Neuroscience 19 43-54
http://dx.doi.org/10.1111/j.1460-9568.2004.03081.x

Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, Velez P, Distelhorst CW (2004) Bcl-2 functionally interacts with inositol 1,4,5-trisphospate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.
Journal of Cell Biology 166 193-203
http://dx.doi.org/10.1083/jcb.200309146

Christova Y, James PS, Jones R (2004) Lipid diffusion in sperm plasma membranes exposed to peroxidative injury from oxygen free radicals.
Molecular Reproduction and Development 68 365-372
http://dx.doi.org/10.1002/mrd.20084

Christova Y, James PS, Mackie A, Cooper TG, Jones R (2004) Molecular diffusion in sperm plasma membranes during epididymal maturation.
Molecular and Cellular Endocrinology 216 41-46
http://dx.doi.org/10.1016/j.mce.2003.10.075

Cobb LJ, Salih DAM, Gonzalez I, Tripathi G, Carter EJ, Lovett FA, Holding C, Pell JM (2004) Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function.
Journal of Cell Science 117 1737-1746
http://dx.doi.org/10.1242/jcs.01028

Coleman MP, Ribchester RR (2004) Programmed axon death, synaptic dysfunction and the ubiquitin proteasome system.
Current Drug Targets - CNS and Neurological Disorders 3 227-238
http://www.bentham.org/cdtcnsnd/contabs/cdtcnsnd3-3.htm#link7

Constancia M, Kelsey GD, Reik W (2004) Resourceful imprinting.
Nature 432 53-57
http://dx.doi.org/10.1038/432053a

Culetto E, Baylis HA, Richmond JE, Jones AK, Fleming JT, Squire MD, Lewis JA, Sattelle DB (2004) The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor α subunit.
Journal of Biological Chemistry 279 42476-42483
http://dx.doi.org/10.1074/jbc.M404370200

Da Costa APC, Leigh AE, Man M-S, Kendrick KM (2004) Face pictures reduce behavioural, autonomic, endocrine and neural indices of stress and fear in sheep.
Proceedings of the Royal Society B: Biological Sciences 271 2077-2084
http://dx.doi.org/10.1098/rspb.2004.2831

Davies W, Smith RJ, Kelsey GD, Wilkinson LS (2004) Expression patterns of the novel imprinted genes Nap1l5 and Peg13 and their non-imprinted host genes in the adult mouse brain.
Gene Expression Patterns 4 741-747
http://dx.doi.org/10.1016/j.modgep.2004.03.008

Delon C, Manifava M, Wood EJ, Thompson D, Krugmann S, Pyne S, Ktistakis NT (2004) Sphingosine kinase 1 is an intracellular effector of phosphatidic acid.
Journal of Biological Chemistry 279 44763-44774
http://dx.doi.org/10.1074/jbc.M405771200

Di Meglio S, Tramontano F, Cimmino G, Jones R, Quesada P (2004) Dual role for poly(ADP-ribose)polymerase-1 and -2 and poly(ADP-ribose)glycohydrolase as DNA-repair and pro-apoptotic factors in rat germinal cells exposed to nitric oxide donors.
Biochimica et Biophysica Acta - Molecular Cell Research 1692 35-44 (Correction: Biochmica et Biophysica Acta - Molecular Cell Research, 2004, vol. 1693, no. 3, p. 213)
http://dx.doi.org/10.1016/j.bbamcr.2004.04.002

Donald S, Hill K, Lecureuil C, Barnouin R, Krugmann S, Coadwell WJ, Andrews SR, Walker SA, Hawkins PT, Stephens LR, Welch HCE (2004) P-Rex2, a new guanine-nucleotide exchange factor for Rac.
FEBS Letters 572 172-176
http://dx.doi.org/10.1016/j.febslet.2004.06.096

Dwyer CM, Gilbert CL, Lawrence AB (2004) Prepartum plasma estradiol and postpartum cortisol, but not oxytocin, are associated with interindividual and breed differences in the expression of maternal behaviour in sheep.
Hormones and Behavior 46 529-543
http://dx.doi.org/10.1016/j.yhbeh.2004.05.011

Erlandsson L, Licence ST, Gaspal F, Bell S, Lane P, Corcoran AE, Martensson I-L (2004) Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient mice.
European Journal of Immunology 34 3595-3603
http://dx.doi.org/10.1002/eji.200425217

Evans NP, North T, Dye S, Sweeney T (2004) Differential effects of the endocrine-disrupting compounds Bisphenol-A and Octylphenol on gonadotropin secretion, in prepubertal ewe lambs.
Domestic Animal Endocrinology 26 61-73
http://dx.doi.org/10.1016/j.domaniend.2003.09.005

Evans PC, Ovaa H, Hamon M, Kilshaw PJ, Hamm S, Bauer S, Ploegh HL, Smith TS (2004) Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.
Biochemical Journal 378 727-734
http://dx.doi.org/10.1042/BJ20031377

Ford S, Antoniou A, Butcher GW, Powis SJ (2004) Competition for access to the rat major histocompatibility complex class I peptide-loading complex reveals optimization of peptide cargo in the absence of transporter associated with antigen processing (TAP) association.
Journal of Biological Chemistry 279 16077-16082
http://dx.doi.org/10.1074/jbc.M400456200

Galler GR, Mundt CA, Parker MJD, Pelanda R, Martensson I-L, Winkler TH (2004) Surface μ heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components.
Journal of Experimental Medicine 199 1523-1532
http://dx.doi.org/10.1084/jem.20031523

Gaunt SJ, Cockley A, Drage D (2004) Additional enhancer copies, with intact cdx protein binding sites, anteriorize Hoxa-7/lacZ expression in mouse embryos: evidence in keeping with an instructional cdx gradient.
International Journal of Developmental Biology 48 613-622
http://dx.doi.org/10.1387/ijdb.041829sg

Giudici M-L, Emson PC, Irvine RF (2004) A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform γ.
Biochemical Journal 379 489-496
http://dx.doi.org/10.1042/BJ20031394

Gonzalez I, Tripathi G, Carter EJ, Cobb LJ, Salih DAM, Lovett FA, Holding C, Pell JM (2004) Akt2: a novel functional link between p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in myogenesis.
Molecular and Cellular Biology 24 3607-3622
http://dx.doi.org/10.1128/MCB.24.9.3607-3622.2004

Han S-K, Todman MG, Herbison AE (2004) Endogenous GABA release inhibits the firing of adult gonadotropin-releasing hormone neurons.
Endocrinology 145 495-499
http://dx.doi.org/10.1210/en.2003-1333

Hanson CJ, Bootman MD, Roderick HL (2004) Cell signlling: IP3 receptors channel calcium into cell death.
Current Biology 14 R933-R935
http://dx.doi.org/10.1016/j.cub.2004.10.019

Harrison RAP (2004) Rapid PKA-catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonate.
Molecular Reproduction and Development 67 337-352
http://dx.doi.org/10.1002/mrd.20028

Hathway GJ, Humphrey PPA, Kendrick KM (2004) Somatostatin induces striatal dopamine release and contralateral turning behaviour in the mouse.
Neuroscience Letters 358 127-131
http://dx.doi.org/10.1016/j.neulet.2003.09.056

Hebeis BJ, Vigorito E, Turner M (2004) The p110δ subunit of phosphoinositide 3-kinase is required for the lipopolysaccharide response of mouse B cells.
Biochemical Society Transactions 32 789-791
http://www.biochemsoctrans.org/bst/032/bst0320789.htm

Hemberger M, Hughes M, Cross JC (2004) Trophoblast stem cells differentiate in vitro into invasive trophoblast giant cells.
Developmental Biology 271 362-371
http://dx.doi.org/10.1016/j.ydbio.2004.03.040

Huang JT, Lee V (2004) Identification and characterization of a novel human FOXK1 gene in silico.
International Journal of Oncology 25 751-757
http://histology1.med.uoc.gr/ijo/2004/volume25/number3/751.pdf

Isles AR, Davies W, Burrmann D, Burgoyne PS, Wilkinson LS (2004) Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome.
Human Molecular Genetics 13 1849-1855
http://dx.doi.org/10.1093/hmg/ddh203

Isles AR, Humby T, Walters DE, Wilkinson LS (2004) Common genetic effects on variation in impulsivity and activity in mice.
Journal of Neuroscience 24 6733-6740
http://dx.doi.org/10.1523/JNEUROSCI.1650-04.2004

James PS, Hennessy C, Berge T, Jones R (2004) Compartmentalisation of the sperm plasma membrane: a FRAP, FLIP and SPFI analysis of putative diffusion barriers on the sperm head.
Journal of Cell Science 117 6485-6495
http://dx.doi.org/10.1242/jcs.01578

Jones R (2004) Sperm survival versus degradation in the mammalian epididymis: an hypothesis.
Biology of Reproduction 71 1405-1411
http://dx.doi.org/10.1095/biolreprod.104.031252

Kasri NN, Holmes AM, Bultynck G, Parys JB, Bootman MD, Rietdorf K, Missiaen L, McDonald F, De Smedt H, Conway SJ, Holmes AB, Berridge MJ, Roderick HL (2004) Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.
EMBO Journal 23 312-321
http://dx.doi.org/10.1038/sj.emboj.7600037

Krugmann S, Williams R, Stephens LR, Hawkins PT (2004) ARAP3 is a PI3K- and Rap-regulated GAP for RhoA.
Current Biology 14 1380-1384
http://dx.doi.org/10.1016/j.cub.2004.07.058

Lewis AJ, Mitsuya K, Constancia M, Reik W (2004) Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region.
Molecular and Cellular Biology 24 5650-5656
http://dx.doi.org/10.1128/MCB.24.13.5650-5656.2004

Lewis AJ, Mitsuya K, Umlauf D, Smith P, Dean WL, Walter J, Higgins M, Feil R, Reik W (2004) Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.
Nature Genetics 36 1291-1295
http://dx.doi.org/10.1038/ng1468

Lewis AJ, Murrell AM (2004) Genomic imprinting: CTCF protects the boundaries.
Current Biology 14 R284-R286
http://dx.doi.org/10.1016/j.cub.2004.03.026

Ley R, Ewings KE, Hadfield K, Howes EA, Balmanno K, Cook SJ (2004) Extracellular signal-related kinases 1/2 are serum-stimulated "BimEL-kinases" that bind to the BH3-only protein BimEL causing its phosphorylation and turnover.
Journal of Biological Chemistry 279 8837-8847
http://dx.doi.org/10.1074/jbc.M311578200

Li X, Dai Y-F, Allen WR (2004) Influence of insulin-like growth factor-I on cytoplasmic maturation of horse oocytes in vitro and organization of the first cell cycle following nuclear transfer and parthenogenesis.
Biology of Reproduction 71 1391-1396
http://dx.doi.org/10.1095/biolreprod.104.029066

Liu YP, Wilkinson LS, Robbins TW (2004) Effects of acute and chronic buspirone on impulsive choice and efflux of 5-HT and dopamine in hippocampus, nucleus accumbens and prefrontal cortex.
Psychopharmacology 173 175-185
http://dx.doi.org/10.1007/s00213-003-1726-1

Loewen CJR, Gaspar ML, Jesch SA, Delon C, Ktistakis NT, Henry SA, Levine TP (2004) Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid.
Science 304 1644-1647
http://dx.doi.org/10.1126/science.1096083

Ma D, Shield JPH, Dean WL, Leclerc I, Knauf C, Burcelin R, Rutter GA, Kelsey GD (2004) Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.
Journal of Clinical Investigation 114 339-348
http://dx.doi.org/10.1172/JCI200419876

Mackenzie L, Roderick HL, Berridge MJ, Conway SJ, Bootman MD (2004) The spatial pattern of atrial cardiomyocyte calcium signalling modulates contraction.
Journal of Cell Science 117 6327-6337
http://dx.doi.org/10.1242/jcs.01559

Mackenzie L, Roderick HL, Proven A, Conway SJ, Bootman MD (2004) Inositol 1,4,5-trisphosphate receptors in the heart.
Biological Research 37 553-557
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400008&lng=es&nrm=iso&tlng=en

McNeill L, Cassady RL, Sarkardei S, Cooper JC, Morgan G, Alexander DR (2004) CD45 isoforms in T cell signalling and development.
Immunology Letters 92 125-134
http://dx.doi.org/10.1016/j.imlet.2003.10.018

Meade JL, Tybulewicz VLJ, Turner M (2004) The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.
European Journal of Immunology 34 1102-1110
http://dx.doi.org/10.1002/eji.200324309

Meredith RM, McCabe BJ, Kendrick KM, Horn G (2004) Amino acid neurotransmitter release and learning: a study of visual imprinting.
Neuroscience 126 249-256
http://dx.doi.org/10.1016/j.neuroscience.2004.03.046

Mimmack ML, Brooking J, Bahn S (2004) Quantitative polymerase chain reaction: validation of microarray results from postmortem brain studies.
Biological Psychiatry 55 337-345
http://dx.doi.org/10.1016/j.biopsych.2003.09.007

Moos F, Fontanaud P, Mekaouche M, Brown D (2004) Oxytocin neurones are recruited into co-ordinated fluctuations of firing before bursting in the rat.
Neuroscience 125 391-410
http://dx.doi.org/10.1016/j.neuroscience.2004.01.033

Morgan HD, Dean WL, Coker HA, Reik W, Petersen-Mahrt SK (2004) Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming.
Journal of Biological Chemistry 279 52353-52360
http://dx.doi.org/10.1074/jbc.M407695200

Murrell AM, Heeson S, Cooper WN, Douglas E, Apostolidou S, Moore GE, Maher ER, Reik W (2004) An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype.
Human Molecular Genetics 13 247-255
http://dx.doi.org/10.1093/hmg/ddh013

Murrell AM, Heeson S, Reik W (2004) Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops.
Nature Genetics 36 889-893
http://dx.doi.org/10.1038/ng1402

Nielsen MO, Nyborg S, Jakobsen K, Fleet IR, Norgaard J (2004) Mammary uptake and excretion of prostanoids in relation to mammary blood flow and milk yield during pregnancy-lactation and somatotropin treatment in dairy goats.
Domestic Animal Endocrinology 27 345-362
http://dx.doi.org/10.1016/j.domaniend.2004.04.003

Odeh H, Hagiwara N, Skynner MJ, Mitchem KL, Beyer LA, Allen ND, Brilliant MH, Lebart MC, Dolan DF, Raphael Y, Kohrman DC (2004) Characterization of two transgene insertional mutations at piroutte, a mouse deafness locus.
Audiology and Neuro-Otology 9 303-314
http://dx.doi.org/10.1159/000080701

Okkenhaug K, Bilancio A, Emery JL, Vanhaesebroeck B (2004) Phosphoinositide 3-kinase in T cell activation and survival.
Biochemical Society Transactions 32 332-335
http://www.biochemsoctrans.org/bst/032/bst0320332.htm

Osborne CS, Chakalova L, Brown KE, Carter D, Horton A, Debrand E, Goyenechea B, Mitchell JA, Lopes S, Reik W, Fraser P (2004) Active genes dynamically co-localize to shared sites of ongoing transcription.
Nature Genetics 36 1065-1071
http://dx.doi.org/10.1038/ng1423

Padinjat R, Andrews SR (2004) TRP channels at a glance.
Journal of Cell Science 117 5707-5709
http://dx.doi.org/10.1242/10.1242/jcs.01343

Pascall JC, Brown KD (2004) Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2.
Biochemical and Biophysical Research Communications 317 244-252
http://dx.doi.org/10.1016/j.bbrc.2004.03.039

Pearce AC, Senis YA, Billadeau DD, Turner M, Watson SP, Vigorito E (2004) Vav1 and Vav3 have critical but redundant roles in mediating platelet activation by collagen.
Journal of Biological Chemistry 279 53955-53962
http://dx.doi.org/10.1074/jbc.M410355200

Peppiatt CM, Holmes AM, Seo JT, Bootman MD, Collins TJ, McDonald F, Roderick HL (2004) Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.
Biochemical Journal 381 929-939
http://dx.doi.org/10.1042/BJ20040097

Petrunkina AM, Harrison RAP, Ekhlasi-Hundrieser M, Topfer-Petersen E (2004) Role of volume-stimulated osmolyte and anion channels in volume regulation by mammalian sperm.
Molecular Human Reproduction 10 815-823
http://dx.doi.org/10.1093/molehr/gah106

Petrunkina AM, Radcke S, Gunzel-Apel A-R, Harrison RAP, Topfer-Petersen E (2004) Role of potassium channels, the sodium-potassium pump and the cytoskeleton in the control of dog sperm volume.
Theriogenology 61 35-54
http://dx.doi.org/10.1016/S0093-691X(03)00184-5

Plagge A, Gordon E, Dean WL, Boiani R, Cinti S, Peters J, Kelsey GD (2004) The imprinted signalling protein XLαs is required for postnatal adaptation to feeding.
Nature Genetics 36 818-826
http://dx.doi.org/10.1038/ng1397

Prabakaran S, Swatton JE, Ryan MM, Huffaker SJ, Huang JT-J, Griffin JL, Wayland M, Freeman T, Dudbridge F, Lilley KS, Karp NA, Hester S, Tkachev D, Mimmack ML, Yolken RH, Webster MJ, Torrey EF, Bahn S (2004) Mitochondrial dysfunction in Schizophrenia: evidence for compromised brain metabolism and oxidative stress.
Molecular Psychiatry 9 684-697
http://dx.doi.org/10.1038/sj.mp.4001511

Puri KD, Doggett TA, Douangpanya J, Hou Y, Tino WT, Wilson T, Graf T, Clayton E, Turner M, Hayflick JS, Diacovo TG (2004) Mechanisms and implications of phosphoinositide 3-kinase δ in promoting neutrophil trafficking into inflamed tissue.
Blood 103 3448-3456
http://dx.doi.org/10.1182/blood-2003-05-1667

Reale V, Chatwin HM, Evans PD (2004) The activation of G-protein gated inwardly rectifying K+ channels by a cloned Drosophila melanogaster neuropeptide F-like receptor.
European Journal of Neuroscience 19 570-576
http://dx.doi.org/10.1111/j.0953-816X.2003.03141.x

Reif K, Okkenhaug K, Sasaki T, Penninger JM, Vanhaesbroeck B, Cyster JG (2004) Differential roles for phosphoinositide 3-kinases, p110γ and p110δ, in lymphocyte chemotaxis and homing.
Journal of Immunology 173 2236-2240
http://www.jimmunol.org/cgi/content/abstract/173/4/2236

Ren L, Zou X, Smith JA, Bruggemann M (2004) Silencing of the immunoglobulin heavy chain locus by removal of all eight constant-region genes in a 200-kb region.
Genomics 84 686-695
http://dx.doi.org/10.1016/j.ygeno.2004.06.008

Rogers SM, Matheson T, Sasaki K, Kendrick KM, Simpson SJ, Burrows M (2004) Substantial changes in central nervous system neurotransmitters and neuromodulators accompany phase change in the locust.
Journal of Experimental Biology 207 3603-3617
http://dx.doi.org/10.1242/jeb.01183

Russell SJ, Ruddock LW, Salo KEH, Oliver JD, Roebuck QP, Llewellyn DH, Roderick HL, Koivunen P, Myllyharju J, High S (2004) The primary substrate binding site in the b' domain of ERp57 is adapted for endoplasmic reticulum lectin association.
Journal of Biological Chemistry 279 18861-18869
http://dx.doi.org/10.1074/jbc.M400575200

Ryan MM, Huffaker SJ, Webster MJ, Wayland M, Freeman T, Bahn S (2004) Application and optimization of microarray technologies for human postmortem brain studies.
Biological Psychiatry 55 329-336
http://dx.doi.org/10.1016/j.biopsych.2003.10.016

Salih DAM, Tripathi G, Holding C, Szestak TAM, Gonzalez MI, Carter EJ, Cobb LJ, Eisemann JE, Pell JM (2004) Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice.
Proceedings of the National Academy of Sciences of the United States of America 101 4314-4319
http://dx.doi.org/10.1073/pnas.0400230101

Santos F, Dean WL (2004) Epigenetic reprogramming during early development in mammals.
Reproduction 127 643-651
http://dx.doi.org/10.1530/rep.1.00221

Scullion S, Brown D, Leng G (2004) Modelling the pituitary response to luteinizing hormone-releasing hormone.
Journal of Neuroendocrinology 16 265-271
http://dx.doi.org/10.1111/j.0953-8194.2004.01169.x

Shadan S, James PS, Howes EA, Jones R (2004) Cholesterol efflux alters lipid raft stability and distribution during capacitation of boar spermatozoa.
Biology of Reproduction 71 253-265
http://dx.doi.org/10.1095/biolreprod.103.026435

Sibley CP, Coan PM, Ferguson-Smith AC, Dean WL, Hughes J, Smith P, Reik W, Burton GJ, Fowden AL, Constancia M (2004) Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placenta.
Proceedings of the National Academy of Sciences of the United States of America 101 8204-8208
http://dx.doi.org/10.1073/pnas.0402508101

Smith RJ, Arnaud P, Kelsey GD (2004) Identification and properties of imprinted genes and their control elements.
Cytogenetic and Genome Research 105 335-345
http://dx.doi.org/10.1159/000078206

Stumm RK, Zhou C, Schulz S, Endres M, Kronenberg G, Allen JP, Tulipano G, Holt V (2004) Somatostatin receptor 2 is activated in cortical neurons and contributes to neurodegeneration after focal ischemia.
Journal of Neuroscience 24 11404-11415
http://dx.doi.org/10.1523/JNEUROSCI.3834-04.2004

Swatton JE, Prabakaran S, Karp NA, Lilley KS, Bahn S (2004) Protein profiling of human postmortem brain using 2-dimensional fluorescence difference gel electrophoresis (2-D DIGE).
Molecular Psychiatry 9 128-143
http://dx.doi.org/10.1038/sj.mp.4001475

Swatton JE, Sellers LA, Faull RLM, Holland A, Iritani S, Bahn S (2004) Increased MAP kinase activity in Alzheimer's and Down Syndrome but not schizophrenia human brain.
European Journal of Neuroscience 19 2711-2719
http://dx.doi.org/10.1111/j.0953-816X.2004.03365.x

Tamura T, Ariga H, Kinashi T, Uehara S, Kikuchi T, Nakada M, Tokunaga T, Xu W, Kariyone A, Saito T, Kitamura T, Maxwell GM, Takaki S, Takatsu K (2004) The role of antigenic peptide in CD4+ T helper phenotype development in a T cell receptor transgenic model.
International Immunology 16 1691-1699
http://dx.doi.org/10.1093/intimm/dxh170

Testerink C, Dekker HL, Lim Z-Y, Johns MK, Holmes AB, De Koster CG, Ktistakis NT, Munnik T (2004) Isolation and identification of phosphatidic acid targets from plants.
Plant Journal 39 527-536
http://dx.doi.org/10.1111/j.1365-313X.2004.02152.x

Todd DE, Densham RM, Molton SA, Balmanno K, Newson C, Weston CR, Garner AP, Scott L, Cook SJ (2004) ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrest.
Oncogene 23 3284-3295
http://dx.doi.org/10.1038/sj.onc.1207467

Trabace L, Cassano T, Tucci P, Steardo L, Kendrick KM, Cuomo V (2004) The effects of nitric oxide on striatal serotoninergic transmission involve multiple targets: an in vivo microdialysis study in the awake rat.
Brain Research 1008 293-298
http://dx.doi.org/10.1016/j.brainres.2004.01.090

Vigorito E, Bardi G, Glassford J, Lam EW-F, Clayton E, Turner M (2004) Vav-dependent and Vav-independent phosphatidylinositol 3-kinase activation in murine B cells determined by the nature of the stimulus.
Journal of Immunology 173 3209-3214
http://www.jimmunol.org/cgi/content/abstract/173/5/3209

Vigorito E, Bell S, Hebeis BJ, Reynolds H, McAdam S, Emson PC, McKenzie A, Turner M (2004) Immunological function in mice lacking the Rac-related GTPase RhoG.
Molecular and Cellular Biology 24 719-729
http://dx.doi.org/10.1128/MCB.24.2.719-729.2004

Vigorito E, Clayton E, Turner M (2004) BCR activatation of PI3K is Vav-independent in murine B cells.
Biochemical Society Transactions 32 781-784
http://www.biochemsoctrans.org/bst/032/bst0320781.htm

Waldvogel HJ, Billinton A, White JH, Emson PC, Faull RLM (2004) Comparative cellular distribution of GABAA and GABAB receptors in the human basal ganglia: immunohistochemical colocalization of the α1 subunit of the GABAA receptor, and the GABABR1 and GABABR2 receptor subunits.
Journal of Comparative Neurology 470 339-356
http://dx.doi.org/10.1002/cne.20005

Walker SA, Kupzig S, Bouyoucef D, Davies LC, Tsuboi T, Bivona TG, Cozier GE, Lockyer PJ, Buckler A, Rutter GA, Allen MJ, Phillips MR, Cullen PJ (2004) Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations.
EMBO Journal 23 1749-1760
http://dx.doi.org/10.1038/sj.emboj.7600197

Walker SA, Lockyer PJ (2004) Visualizing Ras signalling in real-time.
Journal of Cell Science 117 2879-2886
http://dx.doi.org/10.1242/10.1242/jcs.01285

Walters DE, Edwards RG (2004) Further thoughts regarding evidence offered in support of the `Barker hypothesis'.
Reproductive BioMedicine Online 9 129-131
http://www.rbmonline.com/4DCGI/Article/Detail?38%091%09=%201327%09

Williamson CM, Ball ST, Nottingham WT, Skinner JA, Plagge A, Turner MD, Powles N, Hough T, Papworth D, Fraser WD, Maconochie M, Peters J (2004) A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas.
Nature Genetics 36 894-899
http://dx.doi.org/10.1038/ng1398

Wilson KE, Ryan MM, Prime JE, Pashby DP, Orange PR, O'Beirne G, Whateley JG, Bahn S, Morris CM (2004) Functional genomics and proteomics: application in neurosciences.
Journal of Neurology, Neurosurgery and Psychiatry 75 529-538
http://jnnp.bmj.com/cgi/content/abstract/75/4/529

Zakaria S, Gomez TS, Savoy DN, McAdam S, Turner M, Abraham RT, Billadeau DD (2004) Differential regulation of TCR-mediated gene transcription by Vav family members.
Journal of Experimental Medicine 199 429-434
http://dx.doi.org/10.1084/jem.20031228

Zhang H, Jones R, Martin-DeLeon PA (2004) Expression and secretion of rat SPAM1(2B1 or PH-20) in the epididymis: role of testicular lumicrine factors.
Matrix Biology 22 653-661
http://dx.doi.org/10.1016/j.matbio.2003.11.010

Zhao R, Yang FT, Alexander DR (2004) An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation.
Cancer Cell 5 37-49
http://dx.doi.org/10.1016/S1535-6108(03)00333-7