Recent selected publications
Lawson CD, Donald S, Anderson KE, Patton DT, Welch HCE
(2011) P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.
Journal of Immunology 186 1467-1476
http://dx.doi.org/10.4049/jimmunol.1002738
Jackson C, Welch HCE, Bellamy TC
(2010)
Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.
PLoS ONE 5 e11962
http://dx.doi.org/10.1371/journal.pone.0011962
Donald S, Humby T, Fyfe I, Segonds-Pichon A, Walker SA, Andrews SR, Coadwell WJ, Emson PC, Wilkinson LS, Welch HCE
(2008) P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.
Proceedings of the National Academy of Sciences of the United States of America 105 4483-4488
http://dx.doi.org/10.1073/pnas.0712324105
Barber MA, Donald S, Thelen S, Anderson KE, Thelen M, Welch HCE
(2007) Membrane translocation of P-Rex1 is mediated by G protein βγ subunits and phosphoinositide 3-kinase.
Journal of Biological Chemistry 282 29967-29976
http://dx.doi.org/10.1074/jbc.M701877200
Welch HCE, Condliffe AM, Milne LJ, Ferguson GJ, Hill K, Webb LMC, Okkenhaug K, Coadwell WJ, Andrews SR, Thelen M, Jones GE, Hawkins PT, Stephens LR
(2005) P-Rex1 regulates neutrophil function.
Current Biology 15 1867-1873
http://dx.doi.org/10.1016/j.cub.2005.09.050
Hill K, Krugmann S, Andrews SR, Coadwell WJ, Finan P, Welch HCE, Hawkins PT, Stephens LR
(2005) Regulation of P-Rex1 by phosphatidylinositol(3,4,5)-trisphosphate and Gβγ subunits.
Journal of Biological Chemistry 280 4166-4173
http://dx.doi.org/10.1074/jbc.M411262200
Welch HCE, Coadwell WJ, Ellson CD, Ferguson GJ, Andrews SR, Erdjument-Bromage H, Tempst P, Hawkins PT, Stephens LR
(2002) P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac.
Cell 108 809-821
http://dx.doi.org/10.1016/S0092-8674(02)00663-3
Updated 24 August, 2011