Publications
Bootman MD, Smyrnias I, Thul R, Coombes S, Roderick HL (2011) Atrial cardiomyocyte calcium signalling.
Biochimica et Biophysica Acta - Molecular Cell Research 1813 922-934
http://dx.doi.org/10.1016/j.bbamcr.2011.01.030
Harzheim D, Talasila A, Movassagh M, Foo RS-Y, Figg N, Bootman MD, Roderick HL (2010) Elevated InsP3R expression underlies enhanced calcium fluxes and spontaneous extra-systolic calcium release events in hypertrophic cardiac myocytes.
Channels 4 55-59
http://www.landesbioscience.com/journals/channels/article/10531
Smyrnias I, Mair W, Harzheim D, Walker SA, Roderick HL, Bootman MD (2010) Comparison of the T-tubule system in adult rat ventricular and atrial myocytes, and its role in excitation-contraction coupling and inotropic stimulation.
Cell Calcium 47 210-223
http://dx.doi.org/10.1016/j.ceca.2009.10.001
Bootman MD, Fearnley CJ, Smyrnias I, MacDonald F, Roderick HL (2009) An update in nuclear calcium signalling.
Journal of Cell Science 122 2337-2350
http://dx.doi.org/10.1242/jcs.028100
Harzheim D, Movassagh M, Foo RS-Y, Ritter O, Tashfeen A, Conway SJ, Bootman MD, Roderick HL (2009) Increased InsP3Rs in the junctional sarcoplasmic reticulum augment Ca2+ transients and arrhythmias associated with cardiac hypertrophy.
Proceedings of the National Academy of Sciences of the United States of America 106 11406-11411
http://dx.doi.org/10.1073/pnas.0905485106
Higazi DR, Fearnley CJ, Drawnel FM, Talasila A, Corps EM, Ritter O, McDonald F, Mikoshiba K, Bootman MD, Roderick HL (2009) Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes.
Molecular Cell 33 472-482
http://dx.doi.org/10.1016/j.molcel.2009.02.005
Rong Y-P, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW (2009) The BH4 domain of Bc1-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.
Proceedings of the National Academy of Sciences of the United States of America 106 14397-14402
http://dx.doi.org/10.1073/pnas.0907555106
Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT (2008) Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.
Journal of Cell Biology 182 685-701
http://dx.doi.org/10.1083/jcb.200803137
Hanson CJ, Bootman MD, Distelhorst CW, Wojcikiewicz RJ, Roderick HL (2008) Bcl-2 supresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content.
Cell Calcium 44 324-338
http://dx.doi.org/10.1016/j.ceca.2008.01.003
Kockskamper J, Zima AV, Roderick HL, Pieske B, Blatter LA, Bootman MD (2008) Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes.
Journal of Molecular and Cellular Cardiology 45 128-147
http://dx.doi.org/10.1016/j.yjmcc.2008.05.014
Roderick HL, Cook SJ (2008) Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival.
Nature Reviews Cancer 8 361-375
http://dx.doi.org/10.1038/nrc2374
Rong Y-P, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW (2008) Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.
Molecular Cell 31 255-265
http://dx.doi.org/10.1016/j.molcel.2008.06.014
Szado T, Vanderheyden V, Parys JB, De Smedt H, Rietdorf K, Kotelevets L, Chastre E, Khan F, Landegren U, Soderberg O, Bootman MD, Roderick HL (2008) Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 105 2427-2432
http://dx.doi.org/10.1073/pnas.0711324105
Roderick HL, Higazi DR, Smyrnias I, Fearnley C, Harzheim D, Bootman MD (2007) Calcium in the heart: when it's good, it's very very good, but when it's bad, it's horrid.
Biochemical Society Transactions 35 957-961
http://dx.doi.org/10.1042/BST0350957
Bootman MD, Higazi DR, Coombes S, Roderick HL (2006) Calcium signalling during excitation-contraction coupling in mammalian atrial myocytes.
Journal of Cell Science 119 3915-3925
http://dx.doi.org/10.1242/jcs.03223
Conway SJ, Thuring JW, Andreu S, Kvinlaug BT, Roderick HL, Bootman MD, Holmes AB (2006) The synthesis of membrane permeant derivatives of myo-inositol 1,4,5-trisphosphate.
Australian Journal of Chemistry 59 887-893
http://dx.doi.org/10.1071/CH06357
Proven A, Roderick HL, Conway SJ, Berridge MJ, Horton JK, Capper SJ, Bootman MD (2006) Inositol 1,4,5-trisphosphate supports the arrhythmogenic action of endothelin-1 on ventricular cardiac myocytes.
Journal of Cell Science 119 3363-3375
http://dx.doi.org/10.1242/jcs.03073
Hanson CJ, Bootman MD, Roderick HL (2004) Cell signlling: IP3 receptors channel calcium into cell death.
Current Biology 14 R933-R935
http://dx.doi.org/10.1016/j.cub.2004.10.019
Kasri NN, Holmes AM, Bultynck G, Parys JB, Bootman MD, Rietdorf K, Missiaen L, McDonald F, De Smedt H, Conway SJ, Holmes AB, Berridge MJ, Roderick HL (2004) Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.
EMBO Journal 23 312-321
http://dx.doi.org/10.1038/sj.emboj.7600037
Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: dynamics, homeostasis and remodelling.
Nature Reviews Molecular Cell Biology 4 517-529
http://dx.doi.org/10.1038/nrm1155
Roderick HL, Lechleiter JD, Camacho P (2000) Cytosolic phosphorylation of calnexin controls intracellular Ca2+ oscillations via an interaction with Serca2b.
Journal of Cell Biology 149 1235-1248.
http://dx.doi.org/10.1083/jcb.149.6.1235
Updated 23 August, 2011