Recent selected publications
Bernardo AS, Faial T, Gardner L, Niakan KK, Ortmann D, Senner CE, Callery EM, Trotter MW, Hemberger MC, Smith JC, Bardwell L, Moffett A, Pedersen RA (2011) BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.
Cell Stem Cell 9 144-155
http://dx.doi.org/10.1016/j.stem.2011.06.015
Madeja Z, Yadi H, Apps R, Boulenouar S, Roper SJ, Gardner L, Moffett A, Colucci F, Hemberger MC (2011) Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth.
Proceedings of the National Academy of Sciences of the United States of America 108 4012-4017
http://dx.doi.org/10.1073/pnas.1005342108
Hemberger MC, Pedersen R (2010) Epigenome disruptors.
Science 330 598-599
http://dx.doi.org/10.1126/science.1199006
Gambardella L, Hemberger MC, Hughes B, Zudaire E, Andrews SR, Vermeren S (2010) PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis.
Science Signaling 3 ra76
http://dx.doi.org/10.1126/scisignal.2001026
Senner CE, Hemberger MC (2010) Regulation of early trophoblast differentiation - lessons from the mouse.
Placenta 31 944-950
http://dx.doi.org/10.1016/j.placenta.2010.07.013
Hemberger MC, Udayashankar R, Tesar P, Moore H, Burton GJ (2010) ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta.
Human Molecular Genetics 19 2456-2467
http://dx.doi.org/10.1093/hmg/ddq128
Hemberger MC (2010) Genetic-epigenetic intersection in trophoblast differentiation: implications for extraembryonic tissue function.
Epigenetics 5 1-6
http://www.landesbioscience.com/journals/epigenetics/article/10589
Hemberger MC, Dean WL, Reik W (2009) Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal.
Nature Reviews Molecular Cell Biology 10 526-537
http://dx.doi.org/10.1038/nrm2727
Roper S, Hemberger MC (2009) Defining pathways that enforce cell lineage specification in early development and stem cells.
Cell Cycle 8 1515-1525
http://www.landesbioscience.com/journals/6/article/8381/
Natale DRC, Hemberger MC, Hughes M, Cross JC (2009) Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate.
Developmental Biology 335 120-131
http://dx.doi.org/10.1016/j.ydbio.2009.08.022
Ng RK, Dean WL, Dawson C, Lucifero D, Madeja Z, Reik W, Hemberger MC (2008) Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.
Nature Cell Biology 10 1280-1290
http://dx.doi.org/10.1038/ncb1786
Screen M, Dean WL, Cross JC, Hemberger MC (2008) Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling.
Development 135 3311-3320
http://dx.doi.org/10.1242/dev.025627
Farthing CR, Ficz G, Ng RK, Chan C-F, Andrews SR, Dean WL, Hemberger MC, Reik W (2008) Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.
PLoS Genetics 4 e1000116
http://dx.doi.org/10.1371/journal.pgen.1000116
Hemberger MC (2007) Epigenetic landscape required for placental development.
Cellular and Molecular Life Sciences 64 2422-2436
http://dx.doi.org/10.1007/S00018-007-7113-z
Varanou A, Withington SL, Lakasing L, Williamson C, Burton GJ, Hemberger MC (2006) The importance of cysteine cathepsin proteases for placental development.
Journal of Molecular Medicine 84 305-317
http://dx.doi.org/10.1007/s00109-005-0032-2
Hemberger MC, Cross JC (2001) Genes governing placental development.
Trends in Endocrinology and Metabolism 12 162-168
http://dx.doi.org/10.1016/S1043-2760(01)00375-7
Updated 6 March, 2012