Life Sciences Research for Lifelong Health

Group Members

Dr Mikhail Spivakov

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Mr Pawel Bednarz

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Dr Jonathan Cairns

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Miss Lina Dobnikar

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Dr Paula Freire Pritchett

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Dr Hashem Koohy

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Joanna Mitchelmore

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Mr Will Orchard

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Michiel Thiecke

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Latest Publications

Platelet function is modified by common sequence variation in megakaryocyte super enhancers.

Petersen R, Lambourne JJ, Javierre BM

Nature communications
8 2041-1723:16058 (2017)

PMID: 28703137

Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation.

Siersbæk R, Madsen JGS, Javierre BM

Molecular cell
66 1097-4164:420-435.e5 (2017)

PMID: 28475875

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells.

Freire-Pritchett P, Schoenfelder S, Várnai C

eLife
6 2050-084X: (2017)

PMID: 28332981

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Javierre BM, Burren OS, Wilder SP

Cell
167 1097-4172:1369-1384.e19 (2016)

PMID: 27863249

Defining cell type with chromatin profiling.

Spivakov M, Fraser P

Nature biotechnology
34 1546-1696:1126-1128 (2016)

PMID: 27824844

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.

Pancaldi V, Carrillo-de-Santa-Pau E, Javierre BM

Genome biology
17 1474-760X:152 (0)

PMID: 27391817

CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data.

Cairns J, Freire-Pritchett P, Wingett SW

Genome biology
17 1474-760X:127 (2016)

PMID: 27306882

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination.

Bolland DJ, Koohy H, Wood AL

Cell reports
15 2211-1247:2475-87 (2016)

PMID: 27264181

CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets.

Schofield EC, Carver T, Achuthan P

Bioinformatics (Oxford, England)
32 1367-4811:2511-3 (2016)

PMID: 27153610

Dynamic Reorganization of Extremely Long-Range Promoter-Promoter Interactions between Two States of Pluripotency.

Joshi O, Wang SY, Kuznetsova T

Cell stem cell
17 1875-9777:748-57 (2015)

PMID: 26637943

A novel phosphate-starvation response in fission yeast requires the endocytic function of Myosin I.

Petrini E, Baillet V, Cridge J

Journal of cell science
1477-9137: (2015)

PMID: 26345368