LABORATORIES:

Developmental Genetics
& Imprinting
 
Wolf Reik
Stephen Gaunt
Myriam Hemberger
Jon Houseley
Gavin Kelsey

Chromatin &
Gene Expression

Peter Fraser
Anne Corcoran
Sarah Elderkin
Cameron Osborne
Patrick Varga Weisz

Lymphocyte Signalling
& Development

Martin Turner
Geoff Butcher
Klaus Okkenhaug
Marc Veldhoen
Elena Vigorito

Molecular Signalling
Simon Cook
Tomas Bellamy
Martin Bootman
Michael Coleman
Keith Kendrick
Jennifer Pell
Llewelyn Roderick

Inositide
Len Stephens
Peter Evans
Phillip Hawkins
Sonja Vermeren
Nicholas Ktistakis
Raghu Padinjat
Michael Wakelam
Heidi Welch



Senior Affiliate Scientists
John Bicknell
Marianne Brüggemann
Piers Emson
Mike Taussig

Emeritus Fellow


Science Services

Postdoc Programme
Mentoring

Research into Action

Scientific Publications


The Laboratory of Lymphocyte Signalling and Development

• Autoimmune diseases
• Inflammatory diseases
• Transplantation
• Tumour immunotherapy
• Enhancing immune responses
• Vaccines

Aims and potential for translation of our research

We study the development and function of lymphocytes with
a view to identifying the molecular pathways that control this
in health and disease.

Current research translation activities

Commercial collaborations
GlaxoSmithKline (Francesco Colucci & Elena Vigorito)
GlaxoSmithKline (Klaus Okkenhaug)
GlaxoSmithKline (Martin Turner)
Merck Serono (Francesco Colucci & Martin Turner)
Merck Serono (Klaus Okkenhaug)
Piramed Pharma (Klaus Okkenhaug)
UCB Celltech (Francesco Colucci & Klaus Okkenhaug)
UCB Celltech (Klaus Okkenhaug)

Marianne Brüggemann, a Group Leader in our Laboratory, has joined BBT Ltd on secondment to pursue translational development of new technologies for monoclonal antibody production.

Matthew Baker, co-founder and CEO of Antitope Ltd, completed his postdoctoral training in our Laboratory.

Clinical and pre-clinical collaborations
Cambridge Institute for Medical Research, University of Cambridge:
MicroRNA (Elena Vigorito & Martin Turner)
 
Department of Haematology, University of Cambridge: BclXl deamidation (Rui Zhao)
 
Dept of Hematology & Clinical Immunology, University of Perugia:
Modulation of transplantation immunity (Francesco Colucci & Klaus Okkenhaug)
 
Dept of Histology & Embryology, University of Rijeka:
Opportunistic infections (Francesco Colucci & Klaus Okkenhaug)
 
Medical Charity Funding
British Heart Foundation:
T cell infiltration in chronic heart allograft rejection (Klaus Okkenhaug)
 
• Details of previous translational activity can be found here

 

 


Lymphocyte signalling and development