Highlight Publication Archive 2009

December 2009
Schoenfelder S,* Sexton T,* Chakalova L,* Cope NF, Horton A, Andrews S, Kurukuti S, Mitchell JA, Umlauf D, Dimitrova DS, Eskiw CH, Luo Y, Wei CL, Ruan Y, Bieker JJ, and Fraser P (2010)
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
Nature Genetics
More details...

June 2009
Dagmar Harzheim, Mehregan Movassagh, Roger Foo, Oliver Ritter, Aslam Tashfeen, Stuart Conway,
Martin Bootman, and Llewelyn Roderick
Increased InsP3Rs in the junctional sarcoplasmic reticulum augment Ca2+ transients and arrhythmias associated with cardiac hypertrophy
PNAS 2009 106:11406-11411
More details...

April 2009
Padinjat R, Coessens E, Manifava M, Georgiev P, Pettitt T, Wood E, Garcia-Murillas I, Okkenhaug H, Trivedi D, Zhang Q, Razzaq A, Zaid O, Wakelam MJO, O'Kane CJ, Ktistakis NT (2009)
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels
Journal of Cell Biology 185 129-145
More details...

April 2009
Tadepally Lakshmikanth, Shannon Burke, Talib Hassan Ali, Silvia Kimpfler, Francesco Ursini, Loredana Ruggeri, Marusca Capanni, Viktor Umansky, Annette Paschen, Antje Sucker, Daniela Pende, Veronika Groh, Roberto Biassoni, Petter Höglund, Masashi Kato, Kazuko Shibuya, Dirk Schadendorf, Andrea Anichini, Soldano Ferrone, Andrea Velardi, Klas Kärre, Akira Shibuya, Ennio Carbone and Francesco Colucci.
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
Advance Online Publication J. Clin. Invest.
http://dx.doi.org/10.1172/JCI36022

Authorship note:
Tadepally Lakshmikanth, Shannon Burke, Ennio Carbone and Francesco Colucci contributed equally to this work.

March 2009
Aurore Saudemont, Fabien Garçon, Hakim Yadi, Marta Roche-Molina, Nayoung Kim, Anne Segonds-Pichon, Alfonso Martín-Fontecha, Klaus Okkenhaug, and Francesco Colucci (2009).
p110γ and p110δ isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.
Proceedings of the National Academy of Sciences of the United States of America 106 5795-5800
More details...

February 2009
Redrup L, Branco MR, Perdeaux ER, Krueger C, Lewis A, Santos F, Nagano T, Cobb BS, Fraser P, Reik W (2009) The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing.
Development 136 525-530
More details...

February 2009
Higazi DR, Fearnley CJ, Drawnel FM, Talasila A, Corps EM, Ritter O, McDonald F, Mikoshiba K, Bootman MD, Roderick HL (2009)
Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes.
Molecular Cell 33 472-482
See news feature...

January 2009
Chotalia M, Smallwood S, Ruf N, Dawson C, Lucifero D, Frontera M, James K, Dean WL, Kelsey GD (2009) Transcription is required for establishment of germline methylation marks at imprinted genes.
Genes and Development 23 105-117
More details...