Highlight Publication Archive 2008

December 2008
Zhao R, Follows GA, Beer PA, Scott LM, Huntly BJP, Green AR, Alexander DR (2008)
Inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders.
New England Journal of Medicine 359 2778-2789
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December 2008
Robert Adalbert, Antal Nogradi, Elisabetta Babetto, Lucie Janeckova, Simon A. Walker, Martin Kerschensteiner, Thomas Misgeld and Michael P. Coleman (In press)
Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies. Brain  (Available online 5th December 2008)
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November 2008
Nagano T, Mitchell JA, Sanz LA, Pauler FM, Ferguson-Smith AC, Feil R and Fraser P (2008)
The Air non-coding RNA epigenetically silences transcription by targeting G9a to chromatin.
Science
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September 2008
Ray Kit Ng, Wendy Dean, Claire Dawson, Diana Lucifero, Zofia Madeja, Wolf Reik & Myriam Hemberger (2008)
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
Nature Cell Biology Published online: 5th October 2008
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For further information, please click here to refer to the press release relating to these findings
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August 2008
Axe AL#, Walker SA#, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT (2008) Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.
Journal of Cell Biology 182 685-701
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July 2008
Farthing CR, Ficz G, Ng RK, Chan C-F, Andrews S, Dean WL, Hemberger M, Reik W (2008)
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.
PLoS Genetics 4 e1000116
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June 2008
Guillaume Smits#, Andrew J Mungall#, Sam Griffiths-Jones, Paul Smith, Delphine Beury, Lucy Matthews, Jane Rogers, Andrew J Pask, Geoff Shaw, John L VandeBerg, John R McCarrey, the SAVOIR Consortium, Marilyn B Renfree, Wolf Reik & Ian Dunham.
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians
Nature Genetics Published online: 29 June 2008
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March 2008
Donald S, Humby T, Fyfe I, Segonds-Pichon A, Walkers SA, Andrews SR, Coadwell WJ, Emson PC, Wilkinson LS, Welch HCE (2008)
P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.
Proceedings of the National Academy of Sciences of the United States of America 105 4483-4488
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February 2008
Szado T, Vanderheyden V, Parys JB, De Smedt H, Rietdorf K, Kotelevets L, Chastre E, Khan F, Landegren U, Soderberg O, Bootman MD, Roderick HL.
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.
Proceedings of the National Academy of Sciences of the United States of America 105 2427-2432
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January 2008
Jennifer Mitchell and Peter Fraser
Transcription factories are nuclear subcompartments that remain in the absence of transcription Genes & Development 22: 20 - 25, 2008
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