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Peter Fraser
Anne Corcoran
Sarah Elderkin
Cameron Osborne
Patrick Varga-Weisz
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Lymphocyte Signalling
& Development
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Tel. (01223) 496644
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Dynamic changes in chromatin and nuclear structure can regulate patterns of cellular gene expression during differentiation and development, or in response to environmental signals. Our research looks at various levels of chromatin, chromosome and nuclear structure, from individual nucleosome modifications to the dynamic 3D structure of chromosomes and their inter-relationships in the nucleus and how they affect genome functions.
Long-range chromatin interactions
Preferential associations between co-regulated genes
at transcription factories
Non-coding RNA and epigenetic silencing of gene expression
Babraham Institute - Babraham Research Campus - Cambridge - United Kingdom